Skin aging and wound treatment using cell migration agents
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Abstract
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A cell migration agent promotes the healing of wounds by promoting movement of fibroblast cells away from the periphery of the wound. The agents can include Indole-3-Acetic acid and its derivatives such as Indole-3-Acetyl-L-Phenylalanine. Significant increases in the migration of fibroblast cells were observed at five days after treatment initiation. When administered in a dosage of between 0.1 and 250 ppm, these compounds appear to have the ability to move healthy human fibroblast cells into areas void of cells more rapidly than if the agent were not present. This results in the plumping of the skin or healing of wounds. The compounds can be delivered by topical or internal methods of application.
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미국특허청에서 퍼온건데여...
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궁금한게 생겨서여... Indole-3-Acetic acid 라는 시약을 사용하는데.
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0.1 and 250 ppmd이라는 농도 규정을 두고 있거든여...
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근데..
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Claims부분에...세부적으로 농도가 또 제시되어있는데...
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11. The method of claim 10 wherein said step of delivering a therapeutically effective dosage comprises delivering between 0.1 and 1000 ppm of the Indole-3-Acetic Acid or its derivatives.
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라고 약간 다른 범위가 또 나와있는데....
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서론에 제시된 내용과 클레임으로 나온 내용과 어떤 차이가 있는건가요?
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실제적으로 이 실험에 이 시약을 이 농도로 사용하는데 있어서
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로얄티를 지불해야하나요?
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자세히 좀 알려주세요.,...
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그럼...부탁드립니다....
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참고로 제가 설명이 부족하다면...
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특허넘버는 6174541입니다...
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