<![CDATA[
<div class="se-component se-quotation se-l-quotation_bubble" id="SE-5bb74038-3a14-4879-84cd-bdaf261bf0ea" style="margin: 40px 0px 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size:12pt; line-height: inherit; font-family: se-nanumgothic, sans-serif; vertical-align: baseline; position: relative; color: rgb(61, 68, 68);"><div class="se-component-content" style="margin: 0px auto; padding: 0px 40px; border: 0px; font: inherit; vertical-align: baseline; max-width: 100%; position: relative;"><div class="se-section se-section-quotation se-l-quotation_bubble" style="margin: 0px auto; padding: 10px 0px 47px; border: 0px; font: inherit; vertical-align: baseline;"><blockquote class="se-quotation-container" style="margin: auto; padding: 22px 21px 27px; border: 5px solid rgb(228, 228, 228); font: inherit; vertical-align: baseline; quotes: none; position: relative; box-sizing: border-box; max-width: 500px; background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;"><div class="se-module se-module-text se-quote" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><p class="se-text-paragraph se-text-paragraph-align- " id="SE-0a7ac52a-c8e7-4255-a5d4-59079765dd87" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap; text-align: center;"><span class="se-fs- se-ff- " id="SE-579d422f-d16b-4aec-b8e7-b8041fa4c025" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: 700; font-stretch: inherit; font-size: 19px; line-height: inherit; font-family: se-nanummyeongjo, serif; vertical-align: baseline;">원발성 경화성 담관염 (PSC)의 경우,</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-45a1bb7c-1bdf-4d2c-979a-c1d078d41f16" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap; text-align: center;"><span class="se-fs- se-ff- " id="SE-b1be50f4-70c1-4fce-9b25-48da20db9fcf" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: 700; font-stretch: inherit; font-size: 19px; line-height: inherit; font-family: se-nanummyeongjo, serif; vertical-align: baseline;">언제 간이식 수술을 고려해야 할까?</span></p></div></blockquote></div></div></div><div class="se-component se-text se-l-default" id="SE-9e10bae4-d6a1-4a09-a37f-6f13f9a9e7a4" style="margin: 40px 0px 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size:12pt; line-height: inherit; font-family: se-nanumgothic, sans-serif; vertical-align: baseline; position: relative; color: rgb(61, 68, 68);"><div class="se-component-content" style="margin: 0px auto; padding: 0px 40px; border: 0px; font: inherit; vertical-align: baseline; max-width: 100%;"><div class="se-section se-section-text se-l-default" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><div class="se-module se-module-text" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><p class="se-text-paragraph se-text-paragraph-align- " id="SE-3583977a-86e3-441e-a1be-f0b525543edf" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-f77114da-6195-4027-aeb8-661fe0437c22" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">2020년 현재까지 PSC의 유일한 완치 방법은 간이식 수술밖에 없습니다. </span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-38f835ef-fc31-4f9f-beb3-a29d6ee9469c" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-5395c1a7-4412-4e4d-a7eb-7f828fbecfea" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">담도가 경화되어 협착되는 진행과정을 막을 수 있는 약물치료는 없으며, 안타깝게도 발병률이 10만 명 당 1~2명꼴로 매우 희귀한 질환이다 보니 치료제 개발 연구가 더딘 것도 현실입니다.</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-50ac7022-6c61-4fd3-87f7-a6c4d4762d5d" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-dd7d8312-5831-468c-966c-98ca22a84983" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">​</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-2e0ad558-71dd-4609-bb1c-74e2d9557963" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-4c3b4785-08e7-48ce-8ad7-d54cff3439ef" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;"><span style="font-weight: 700; background-color: inherit; font-family: inherit;">PSC 환자에게 간이식 수술이 언제 필요한지에 대해서도, 역시 확립된 바는 없습니다.</span></span><span class="se-fs- se-ff- " id="SE-8ea75ef6-8b8a-4496-a2ed-480df1d7f4e3" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;"> 미국과 유럽의 경우 치료 방침도 다르고 간이식 시기와 적응증도 다르게 적용하고 있습니다.</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-7a7757a7-b38e-4d80-866a-0a9b7344edea" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-49cafb55-d34f-49ab-a57d-821887b88271" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">​</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-916dde25-486d-4c89-be88-dff60b3fe7e7" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-3ec7c559-2faf-4b68-a6ba-806b8370db7a" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">세계 유수의 센터에서는 여타 다른 간 질환과 유사한 적응증을 토대로 PSC 환자의 간이식을 진행하고 있습니다. </span></p></div></div></div></div><div class="se-component se-quotation se-l-quotation_underline" id="SE-1ccacaa6-84f6-4ba3-91ac-e66c73b624de" style="margin: 40px 0px 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size:12pt; line-height: inherit; font-family: se-nanumgothic, sans-serif; vertical-align: baseline; position: relative; color: rgb(61, 68, 68);"><div class="se-component-content" style="margin: 0px auto; padding: 0px 40px; border: 0px; font: inherit; vertical-align: baseline; max-width: 100%; position: relative;"><div class="se-section se-section-quotation se-l-quotation_underline" style="margin: 0px auto; padding: 10px 0px; border: 0px; font: inherit; vertical-align: baseline;"><blockquote class="se-quotation-container" style="margin: auto; padding: 35px 0px 20px; border-width: 0px 0px 1px; border-top-style: initial; border-right-style: initial; border-bottom-style: solid; border-left-style: initial; border-top-color: initial; border-right-color: initial; border-bottom-color: rgb(155, 155, 155); border-left-color: initial; border-image: initial; font: inherit; vertical-align: baseline; quotes: none; position: relative; box-sizing: border-box;"><div class="se-module se-module-text se-quote" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><p class="se-text-paragraph se-text-paragraph-align- " id="SE-7161237a-cabc-4f17-8229-35004306584b" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-58a4bdae-ea67-47e5-95bb-1f089435a9ac" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 19px; line-height: inherit; font-family: se-nanummyeongjo, serif; vertical-align: baseline;">간이식 수술을 고려하는 상황</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-98528ed7-c7d8-4218-aadc-2e1999e364c0" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-82611ea2-3950-446e-8703-4335bc15b20a" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 19px; line-height: inherit; font-family: se-nanummyeongjo, serif; vertical-align: baseline;">- 반복적으로 발생하는 세균성 담낭염 Bacterial cholangitis</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-85511846-2f43-4031-87b1-6c2cd1c730ff" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-bdfcbbaf-5a76-41f5-ae2f-c5aeb6de5000" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 19px; line-height: inherit; font-family: se-nanummyeongjo, serif; vertical-align: baseline;">- 진행된 간경화</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-21046b3c-3248-45ef-9860-c020b9d0f554" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-cfefe864-1742-4162-9dd3-4323a9bf3bf1" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 19px; line-height: inherit; font-family: se-nanummyeongjo, serif; vertical-align: baseline;">- 간암의 조기 발견</span></p></div><div class="se-module se-module-text se-cite" style="margin: 16px 0px 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><p class="se-text-paragraph se-text-paragraph-align- " id="SE-4120b0c4-ae05-48d5-83e2-541f595582b4" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.5; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap; color: rgb(119, 119, 119);"><span class="se-fs- se-ff- " id="SE-5f841d91-a0e6-47e1-a8f3-bcf5dcb3abff" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 13px; line-height: inherit; vertical-align: baseline;">* 담도암의 경우, 간이식을 못하는 금기증으로 여겨지나 유럽의 몇몇 센터에서는 항암화학요법과 함께 선택적으로 시행하는 경우도 있다고 보고됨</span></p></div></blockquote></div></div></div><div class="se-component se-text se-l-default" id="SE-15a54c10-c7c5-47c2-9144-3330c959472e" style="margin: 40px 0px 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size:12pt; line-height: inherit; font-family: se-nanumgothic, sans-serif; vertical-align: baseline; position: relative; color: rgb(61, 68, 68);"><div class="se-component-content" style="margin: 0px auto; padding: 0px 40px; border: 0px; font: inherit; vertical-align: baseline; max-width: 100%;"><div class="se-section se-section-text se-l-default" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><div class="se-module se-module-text" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><p class="se-text-paragraph se-text-paragraph-align- " id="SE-d0f20c25-890d-4eaa-bfba-17c2d5239735" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-1cd273ef-963b-49ed-bed4-7bf103ec0554" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;"><span style="font-weight: 700; background-color: inherit; font-family: inherit;">PSC 환자의 간이식 수술의 경우, 여타 간 질환과는 달리 기증이 가능한 공여자의 여부가 시기를 결정하는데 더 큰 영향을 미칩니다.</span></span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-fd171d30-ef62-4c91-abdf-5745f6c5281e" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-a55e64b3-cf6a-4b73-a5d9-97fa50beaa6a" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">​</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-9dadc5f3-6fba-43c7-99bb-2ce46c4c3fa4" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-d46bcf20-57b9-4185-b5d2-44b873fbe930" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">​</span></p></div></div></div></div><div class="se-component se-imageGroup se-l-collage" style="margin: 20px 0px 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size:12pt; line-height: inherit; font-family: se-nanumgothic, sans-serif; vertical-align: baseline; position: relative; color: rgb(61, 68, 68);"><div class="se-component-content se-component-content-fit" style="margin: 0px auto; padding: 0px 40px; border: 0px; font: inherit; vertical-align: baseline; max-width: 100%;"><div class="se-section se-section-imageGroup se-l-collage" id="SE-cf066afb-d4be-4322-a4f1-02d469f028ef" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><div class="se-imageGroup-viewer" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline; overflow-wrap: normal;"><div class="se-imageGroup-container" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><div class="se-imageGroup-item se-imageGroup-col-2" style="margin: 0px; padding: 0px 5px 0px 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: inherit; font-family: inherit; vertical-align: baseline; white-space: nowrap; overflow: hidden;"><div class="se-module se-module-image" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: top; position: relative; display: inline-block; width: 451.25px;"><a href="https://blog.naver.com/PostView.nhn?blogId=shapres&Redirect=View&logNo=221950429740&categoryNo=150&isAfterWrite=true#" id="SE-ccbabdfb-0759-40de-ac76-2b47eff92449" class="se-module-image-link __se_image_link __se_link" data-linktype="img" data-linkdata="{"id" : "SE-ccbabdfb-0759-40de-ac76-2b47eff92449", "src" : "https://postfiles.pstatic.net/MjAyMDA1MDdfMTc2/MDAxNTg4ODM0MDA5MDQ1.2Mcv1HFKWd2HadYXL2cHst17SirlGwSDNlScm74H4-Ig.oxeeP3XvdDmhtRIdsNltgwtaX-l9rlL45xYBwhleLlwg.JPEG.shapres/이미지_1.jpg", "linkUse" : "false", "link" : ""}" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><img src="https://img1.daumcdn.net/relay/cafe/original/?fname=https%3A%2F%2Fpostfiles.pstatic.net%2FMjAyMDA1MDdfMTc2%2FMDAxNTg4ODM0MDA5MDQ1.2Mcv1HFKWd2HadYXL2cHst17SirlGwSDNlScm74H4-Ig.oxeeP3XvdDmhtRIdsNltgwtaX-l9rlL45xYBwhleLlwg.JPEG.shapres%2F%25EC%259D%25B4%25EB%25AF%25B8%25EC%25A7%2580_1.jpg%3Ftype%3Dw966" data-lazy-src="" data-width="587" data-height="778" alt="" class="se-image-resource" style="border: 0px; 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margin: 0px; padding: 0px; font: inherit; vertical-align: top; position: relative; width: 429.734px;"></a></div></div></div></div><div class="se-module se-module-text se-caption" style="margin: 10px auto 20px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline; max-width: 100%;"><p class="se-text-paragraph se-text-paragraph-align- " id="SE-3bd73fe2-4046-4ace-9f57-43f46a7a7573" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.5; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap; text-align: center;"><span class="se-fs- se-ff- " id="SE-fe413213-2ce0-4942-932d-0f126c7b6436" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 13px; line-height: inherit; vertical-align: baseline; color: rgb(85, 85, 85);">PSC에 대한 2017년과 2018년 리뷰 논문</span></p></div></div></div></div><div class="se-component se-text se-l-default" id="SE-e2fd1752-5dc6-4256-a63f-fc248d3f7a29" style="margin: 20px 0px 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size:12pt; line-height: inherit; font-family: se-nanumgothic, sans-serif; vertical-align: baseline; position: relative; color: rgb(61, 68, 68);"><div class="se-component-content" style="margin: 0px auto; padding: 0px 40px; border: 0px; font: inherit; vertical-align: baseline; max-width: 100%;"><div class="se-section se-section-text se-l-default" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><div class="se-module se-module-text" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><p class="se-text-paragraph se-text-paragraph-align- " id="SE-dcb47070-20e8-4698-9dff-54840aae62c9" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-ba7a5e4e-90f4-4115-9c01-25fa797d5650" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">​</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-0b1405a0-4419-4f1b-8f9c-aca603fe6bcb" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-ac6b0405-e9f6-4947-8d03-00f24fbaa40a" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">PSC 환자의 경우, 간이식 혹은 사망까지 평균 기간이 진단 후 13.2년 ~ 21.3년으로 보고하고 있습니다.</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-d09c27b6-7ecc-41f9-8879-5fd72d86e300" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-83a4b67d-d2ad-4782-8d20-e171121e2a71" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">(Journal of Hepatology 2017년 리뷰 논문, Lancet 2018년 리뷰 논문 참조)</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-3ec6bd5a-b9f9-4d05-b5bb-4312520e0df0" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-bbf65f0f-88d0-4b21-b13f-e3dda49c0297" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">​</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-714544bb-964f-454d-908e-6d344794f809" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-f060a75c-9197-404a-bdb1-78f29f902e06" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">PSC 환자들의 주된 사망 이유는 담도암 32%, 간부전 15%, 이식 관련 합병증 9%, 대장암 8%로 조사됩니다. 특히 담도암의 경우, 췌장암과 더불어 조기 발견이 어렵고 예후가 매우 나쁘기 때문에 PSC 진단 시 담도암이 합병되어 있을 경우 치료가 매우 어려워집니다.</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-c69c3efc-b7b6-4601-a9ed-d2c6b6e56d02" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-1126de40-5926-4d3b-8a1e-30606da437d3" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">​</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-eb3f2eb3-3d3c-498d-8d8d-1822f6953ace" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-81ca00dc-071b-4cb2-b927-832bbfdbf04a" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">PSC 환자에게 간이식 수술의 경우, 여타 다른 간 질환과는 달리 간이식 이후의 생존율이 우수한 것으로 밝혀져 있으며 3년 생존율은 85~92% 정도로 보고되고 있습니다. 문제는 간이식 시 10~36%까지 발견되는 담도암이며, 담도암이 합병된 경우 1년 생존율은 30% 정도로 낮습니다. 그래서 몇몇 센터에서는 담도암이 있는 PSC 환자의 경우, 간 이식을 시행하지 않기도 합니다.</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-be31f8dd-71e1-410f-91dc-16228a004427" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-1a07be50-7f28-4aeb-9698-d7e36a01f010" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">​</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-ed340bb2-4d28-476b-aee1-400acfdf130f" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-351e0d7c-6d47-43db-8b5d-ff8547588e17" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">조기에 간이식을 시행하는 것이 수술 위험도를 낮추고, 담도암의 발생을 예방할 수 있는 방법이기 때문에 최근에는 보다 초기에 간이식을 시행하는 사례도 보고되고 있습니다. 하지만 이식 후 발생할 수 있는 합병증과 면역억제제 사용에 의한 대장암 발병 등이 보고 되어 있기 때문에 간이식 시기에 대해서는 의료진의 면밀한 평가와 적합한 공여자 여부에 따라 신중히 결정하는 것이 좋겠습니다.</span></p></div></div></div></div><div class="se-component se-horizontalLine se-l-default" id="SE-c18fdeea-38a7-4022-ae74-3653a239ed26" style="margin: 30px 0px 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size:12pt; line-height: inherit; font-family: se-nanumgothic, sans-serif; vertical-align: baseline; position: relative; color: rgb(61, 68, 68);"><div class="se-component-content" style="margin: 0px auto; padding: 0px 40px; border: 0px; font: inherit; vertical-align: baseline; max-width: 100%;"><div class="se-section se-section-horizontalLine se-l-default se-section-align-center" style="margin: 0px auto; padding: 0px; border: 0px; font: inherit; vertical-align: baseline; width: 220px;"><div class="se-module se-module-horizontalLine" style="margin: 0px; padding: 30px 0px 29px; border: 0px; font: inherit; vertical-align: baseline;"><hr class="se-hr" style="margin: 0px auto; border: 0px; height: 1px; background-color: rgb(221, 221, 221);"></div></div></div></div><div class="se-component se-imageStrip se-imageStrip2 se-l-default" id="SE-ddace6f2-407f-440a-ae27-62cf16bfdc6b" style="margin: 30px 0px 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size:12pt; line-height: inherit; font-family: se-nanumgothic, sans-serif; vertical-align: baseline; position: relative; color: rgb(61, 68, 68);"><div class="se-component-content se-component-content-extend" style="margin: 0px auto; padding: 0px 40px; border: 0px; font: inherit; vertical-align: baseline; max-width: 100%;"><div class="se-section se-section-imageStrip se-l-default" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><div class="se-imageStrip-container se-imageStrip-col-2" style="margin: 0px -40px; padding: 0px 5px 0px 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: inherit; font-family: inherit; vertical-align: baseline; position: relative; white-space: nowrap;"><div class="se-module se-module-image" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: top; display: inline-block; box-sizing: border-box; width: 389.906px;"><a href="https://blog.naver.com/PostView.nhn?blogId=shapres&Redirect=View&logNo=221950429740&categoryNo=150&isAfterWrite=true#" class="se-module-image-link __se_image_link __se_link" data-linktype="img" data-linkdata="{"id" : "SE-2fffa740-59ae-4385-952b-93fe28e343c5", "src" : "https://postfiles.pstatic.net/MjAyMDA1MDdfMTQ0/MDAxNTg4ODM1NDkwMjIx._LC_W5W-mc144O637vVh9uoSwRJRk-Ei6ieSBICVJqUg.-EPcP1t4Oi9dGIUO8eAcb7qPxlVLmWIh93Y07o7iCsMg.JPEG.shapres/20111031__20111101_C07_SP01OEXFAMEp1.jpg", "linkUse" : "false", "link" : ""}" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><img src="https://img1.daumcdn.net/relay/cafe/original/?fname=https%3A%2F%2Fpostfiles.pstatic.net%2FMjAyMDA1MDdfMTQ0%2FMDAxNTg4ODM1NDkwMjIx._LC_W5W-mc144O637vVh9uoSwRJRk-Ei6ieSBICVJqUg.-EPcP1t4Oi9dGIUO8eAcb7qPxlVLmWIh93Y07o7iCsMg.JPEG.shapres%2F20111031__20111101_C07_SP01OEXFAMEp1.jpg%3Ftype%3Dw966" data-lazy-src="" data-width="460" data-height="350" alt="" class="se-image-resource" style="border: 0px; margin: 0px; padding: 0px; font: inherit; vertical-align: top; position: relative; width: 389.906px;"></a></div> <div class="se-module se-module-image" style="margin: 0px 0px 0px 5px; padding: 0px; border: 0px; font: inherit; vertical-align: top; display: inline-block; box-sizing: border-box; width: 571.078px;"><a href="https://blog.naver.com/PostView.nhn?blogId=shapres&Redirect=View&logNo=221950429740&categoryNo=150&isAfterWrite=true#" class="se-module-image-link __se_image_link __se_link" data-linktype="img" data-linkdata="{"id" : "SE-a99680aa-4893-4ea1-9fa6-c44188109c84", "src" : "https://postfiles.pstatic.net/MjAyMDA1MDdfNSAg/MDAxNTg4ODM1NDkwMjIw.WuXjq49XAZBvdp6f5jRARWst8RAkIPwpmC3DWjqb_Bkg.sj2TYrJnv_s9ruFnvsvvNOVDQUio2zazlABVyv43R7wg.JPEG.shapres/IMG_5614-770x400.jpg", "linkUse" : "false", "link" : ""}" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><img src="https://img1.daumcdn.net/relay/cafe/original/?fname=https%3A%2F%2Fpostfiles.pstatic.net%2FMjAyMDA1MDdfNSAg%2FMDAxNTg4ODM1NDkwMjIw.WuXjq49XAZBvdp6f5jRARWst8RAkIPwpmC3DWjqb_Bkg.sj2TYrJnv_s9ruFnvsvvNOVDQUio2zazlABVyv43R7wg.JPEG.shapres%2FIMG_5614-770x400.jpg%3Ftype%3Dw966" data-lazy-src="" data-width="770" data-height="400" alt="" class="se-image-resource" style="border: 0px; margin: 0px; padding: 0px; font: inherit; vertical-align: top; position: relative; width: 571.078px;"></a></div></div><div class="se-module se-module-text se-caption" style="margin: 10px auto 20px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline; max-width: 100%;"><p class="se-text-paragraph se-text-paragraph-align- " id="SE-b856fbb4-fe3e-4b5e-8260-638355e79356" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.5; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap; text-align: center;"><span class="se-fs- se-ff- " id="SE-ad7428f3-1db6-4aa8-98c6-79a0889359e2" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 13px; line-height: inherit; vertical-align: baseline; color: rgb(85, 85, 85);">크리스 클럭 Chris Klug, PSC 환자인 그는 28살인 2000년에 간이식 수술을 받고 2년 뒤, 2002년 동계 올림픽에서 동메달을 획득한 스노보드 선수다.</span></p></div></div></div></div><div class="se-component se-text se-l-default" id="SE-0b57c8dc-7614-42d1-9893-0bd49f71b235" style="margin: 20px 0px 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size:12pt; line-height: inherit; font-family: se-nanumgothic, sans-serif; vertical-align: baseline; position: relative; color: rgb(61, 68, 68);"><div class="se-component-content" style="margin: 0px auto; padding: 0px 40px; border: 0px; font: inherit; vertical-align: baseline; max-width: 100%;"><div class="se-section se-section-text se-l-default" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><div class="se-module se-module-text" style="margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline;"><p class="se-text-paragraph se-text-paragraph-align- " id="SE-5284345c-bd09-48a3-8b18-614d18cd6557" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-0f87816e-e049-4c9b-8e8f-ab0fcb4e7bce" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">미국의 크리스 클럭 Chris Klug (1972년생) 씨는 프로 스노보더 선수로 PSC 진단 이후 그의 나이 28살인 2000년에 간이식 수술을 받았습니다.</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-767f5614-e0b3-4012-9d2e-e43155cf0ecf" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-984db3a9-5877-486a-882f-4a72a40a31c5" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">이후 재활에 힘을 써 2002년 솔트레이크 시티 동계 올림픽에서 스노보드 대회전 (Giant Sialom)에 출전하여 동메달을 획득하며 인간 승리 모습을 보여주었습니다.</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-445344a0-04ce-43dc-aa8b-ebcdd15488ee" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-37bd13aa-bd31-45f7-9c5e-cb098e9520c0" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">​</span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-5287c622-4776-4e99-bb6c-cc719b5a1b5e" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-f2ae89cf-6d47-4b17-850d-f8ce815537b6" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">크리스 클럭 씨는 이후 2003년 크리스 클럭 재단을 설립하였고, 이식 후 20년이 지난 2020년 현재까지 콜로라도 아스펜 (Aspen)에서 가족들과 행복한 삶을 누리며 장기이식에 캠페인을 벌이며 이식 환자와 가족들을 위한 활동을 지속하고 있습니다. </span></p><p class="se-text-paragraph se-text-paragraph-align- " id="SE-aa2a6f87-bf04-4dd7-a9d5-d1633b221d86" style="border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 0px; line-height: 1.8; font-family: inherit; vertical-align: baseline; word-break: break-word; overflow-wrap: break-word; white-space: pre-wrap;"><span class="se-fs- se-ff- " id="SE-0a068ea3-73b8-46a8-84a9-657ede6fba55" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">(참조 </span><span class="se-fs- se-ff- " id="SE-40f68249-96fd-4c3b-8422-662f60bd7395" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;"><a href="https://chrisklugfoundation.org/" class="se-link" target="_blank" style="text-decoration-line: underline; margin: 0px; padding: 0px; border: 0px; font: inherit; vertical-align: baseline; text-decoration-skip-ink: none; word-break: break-all; color: rgb(96, 140, 186) !important;">https://chrisklugfoundation.org/</a></span><span class="se-fs- se-ff- " id="SE-63dc91ad-4637-4045-aaa2-3b18971b2583" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline;">)</span></p></div></div></div></div><p><br></p>
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카페 게시글
이식후 Talk
원발성 경화성 담관염 PSC, 간이식 시기에 관련하여
의학살롱
추천 1
조회 792
20.05.07 16:31
댓글 10
다음검색
첫댓글 정보 주심에 감사합니다.
담관염이 담도염인가요?
네 담관염, 담도염 같은 병명입니다~~
정말 감사합니다 희망적인 글이네요ㅜ PSC는 이식후에 예후가 좋지 않다며 이식을 포기한 남편에게 꼭 보여줘야 겠어요ㅜ
PSC는 담도암만 합병되지 않았다면 이식 후 예후가 두번째로 좋은 질병입니다.
이식 절대 포기하지마세요. 저도 PSC로 이번에 간이식 수술 받았습니다
의학살롱님 회복 잘 되시고 건강하시길 기도하겠습니다. 감사합니다 ㅜ
네 감사합니다ㅎㅎ
제가 환자이기도 하지만 현직 의사에요. 현직의사도 PSC로 망설임없이 간이식받는다고 남편분께 말씀드리시고 슬기로운 투병생활 하셨으면 합니다
아침부터 울컥 눈물이 나네요ㅠ
의학살롱님 말씀처럼 긍정적으로 슬기로운 투병생활 되도록 옆에서 더 노력해야겠어요..큰 희망 주셔서 감사합니다!
네ㅎㅎ종종 후기도 올릴거니깐요ㅎㅎ화이팅하십시오
슬기로운 카페회원이 되어주심에
감사드립니다.
잘 완쾌되시고 행복한 하루되세요.
좋은글 감사합니다.