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긍정적 상승작용을
기대하며
영어 이야기 2296
potentiation
[pəténʃièiʃən]
상승작용 (相乘作用)
우리는 특별한 경우를 제외하고
하락 (下落)은 싫어하고 상승 (上乘)을 선호하다.
그리고 상승을 위해 많고 다른 방법(처방)을 사용하고 있다,
The music therapy was known to induce long-term POTENTIATION in the brain of the patients.
음악 치료는 환자들의 뇌에서 장기적 상승을 유발한다고 알려졌다.
음악 애기가 나오니 이런 생각이 난다
The POTENTIATION of the musician's skills led to a captivating performance.
음악가의 기술 상승은 (우리를) 사로잡은 연주로 이끈다.
potentiation 이 물론 긍정적인 문장에만 쓰이지 않는다
상승을 하기는 하는데 부정적인 것도 없지 않으므로 ~
The sleep deprivation was shown to induce long-term POTENTIATION in the brain of the rats.
잠을 못자게 하는 것은 쥐들의 뇌에서
장기상승을 유발한다는 것을 보여준다.
좀 딴 얘기 같지만 '실험용 쥐'는 참 불쌍하다는 생각이 난다.
Aged rats lose their capacity both to learn new tasks and to show POTENTIATION.
(인간에게 많이 이용당한) 늙은 쥐들은 새로운 임무를 터득하고 상상작용을
배우는 양쪽 모두의 기능을 상실한다.
(쥐만 그런 것은 아니라 한국의 멍청한 정치이는
사람이 60이 넘으면 뇌가 썪는다고 했으나
그 또한 '뇌가 썩을 나이'가 지났다)
나이가 들건 젊건 우리가 뇌관리를 잘 해야 하는데 ~
Meditation and prayer have been found to induce long-term potentiation
and improve focus and attention.
명상과 기도는 장기적 상승효과와 집중력이나
주의를 개선시켜준다는 사실이 들어났다.
좀 엉뚱한 글을 공유하며
오늘의 영어 이야기를 접는다.
훈련받은 개와 그렇지 않은 개를 구별하는 법 ~
훈렵받은 개는 개 주인이나 훈련자가 명령을 해야
행독하는데 (적에 대한 공격) 훈렵받지 않은 개는
혼자가 행동을 결정한다
The POTENTIATION of the dog's training resulted in improved obedience.
개의 훈련은 상승작용은 개선된 복종의 결과를 낳는다
California Eureka
rThe sleep deprivation was shown to ind
uce long-term potentiation in the brain of the rats.
Certain drugs have been found to induce long-term potentiation and enhance learning and memory.
The potentiation of the immune system was achieved through a combination of diet and exercise.
Scientists have discovered that certain stimuli can induce long-term potentiation in the brain.
장기 상
Meditation has been found to induce long-term potentiation and improve focus and attention.
Chronic pain can inhibit the ability to induce long-term potentiation and impair memory.
유발하
손
Meditation has been found to induce long-term potentiation and improve focus and attention.
The potentiation of the musician's skills led to a captivating performance.
The potentiation of the chemical reaction caused a rapid increase in temperature.
The potentiation of the speaker's persuasive techniques convinced the audience.
The potentiation of the student's studying efforts resulted in improved grades.
The potentiation of the company's reputation led to increased customer trust.
The potentiation of the dog's training resulted in improved obedience.
The potentiation of the drug's effects led to increased sedation.
투
The potentiation of the coffee's aroma made it more enticing to drink.
The potentiation of the storm's intensity caused widespread damage.
폭풍의 강도가 강화되면서 광범위한 피해가 발생했다
NEROSCIENCE
"She potentiated her performance by practicing diligently."
The research indicates that regular caffeine users might experience diminished long-term potentiation (LTP), a crucial process for learning and memory.
Brain Brew: How Daily Coffee Habits May
Affect Brain Plasticity
and Learning
FeaturedNeuroscienceOpen Neuroscience Articles·November 25, 2023
Summary:
Researchers explore how chronic caffeine consumption potentially impacts brain plasticity and the effectiveness of repetitive transcranial magnetic stimulation (rTMS).
The research indicates that regular caffeine users might experience diminished long-term potentiation (LTP), a crucial process for learning and memory.
This reduction in brain plasticity suggests that daily caffeine intake could influence cognitive functions and the success of rTMS treatments.
These preliminary findings underscore the need for more extensive research to understand the broader implications of habitual caffeine use on the brain.
Key Facts:
Caffeine’s Role in Brain Plasticity: Caffeine, a common stimulant in coffee and tea, acts as an adenosine receptor antagonist in the brain, influencing synaptic strength and plasticity processes such as long-term potentiation (LTP).
Impact on rTMS Effectiveness: Preliminary studies suggest that chronic caffeine consumption might diminish the brain’s capacity for LTP-like plasticity, potentially impacting the effectiveness of treatments like repetitive transcranial magnetic stimulation (rTMS), which relies on LTP induction.
Need for Further Research: The current findings are based on a small-scale study and highlight the necessity for larger, well-powered studies to conclusively determine the effects of chronic caffeine use on brain plasticity and learning mechanisms.
Source: Neuroscience News
The widespread consumption of caffeine, primarily through coffee and tea, has made it a staple in the daily routines of millions worldwide. Its stimulating effects are well-known, but recent research is shedding light on how this ubiquitous psychostimulant might be influencing one of the brain’s most critical functions: plasticity.
At the heart of this exploration is the understanding that caffeine functions as a competitive, non-selective adenosine receptor antagonist, particularly targeting the A1 and A2A subtypes.
This shows a cup of coffee and a brain.
It raises questions about the long-term cognitive effects of our daily coffee habits and whether modifying these could enhance our brain’s learning capacity. Credit: Neuroscience News
These receptors are deeply involved in the modulation of long-term potentiation (LTP), which is fundamental to learning and memory formation.
LTP is essentially the strengthening of synapses in response to increased activity, a process crucial for the brain’s ability to adapt and learn.
This topic gains complexity and relevance when we consider the effects of caffeine in the context of repetitive transcranial magnetic stimulation (rTMS).
rTMS is a non-invasive method used in treating various neuropsychiatric disorders and is theorized to work through the induction of LTP. This makes the interaction between caffeine and rTMS particularly significant.
The method uses magnetic fields to induce electrical currents in specific brain regions, aiming to modulate cortical excitability – a reflection of brain plasticity.
What’s intriguing is the observed difference in rTMS-induced motor evoked potentials (MEPs) between chronic caffeine users and non-users. MEPs are a measure of corticomotor excitability and are considered to reflect underlying plasticity processes in the brain.
The studies under consideration have found that MEP facilitation, an indicator of increased brain plasticity, is more pronounced in non-caffeine users compared to their caffeine-consuming counterparts. This suggests that regular intake of caffeine might be dampening the brain’s plasticity response.
However, it’s crucial to approach these findings with caution. The research in this field is still in its early stages, and the studies have limitations, including small sample sizes and the complexity of accurately measuring and controlling caffeine consumption.
Additionally, the effects observed in these studies may not directly translate to the broader population or to different contexts of caffeine use and rTMS application.
Despite these caveats, the preliminary data is compelling enough to warrant further investigation. If chronic caffeine consumption does indeed limit the brain’s plasticity, this could have significant implications not just for individuals using rTMS for therapeutic purposes but also for our understanding of learning and memory processes in general.
It raises questions about the long-term cognitive effects of our daily coffee habits and whether modifying these could enhance our brain’s learning capacity.
The way forward is clear: more comprehensive, well-designed studies are needed to unravel the complex relationship between caffeine, brain plasticity, and learning.
Such research would not only deepen our understanding of these fundamental brain processes but also guide the development of more effective therapeutic strategies for neuropsychiatric conditions.
As we continue to explore this intriguing intersection of neuroscience and daily life, one thing is certain – our morning cup of coffee may be doing more than just waking us up; it could be subtly shaping the very way our brain learns and adapts.
About this neuroplasticity and learning research news
Author: Neuroscience News Communications
Source: Neuroscience News
Contact: Neuroscience News Communications – Neuroscience News
Image: The image is credited to Neuroscience News
Original Research: Open access.
“Chronic caffeine consumption curbs rTMS-induced plasticity” by Megan Vigne et al. Frontiers in Psychiatry
Abstract
Chronic caffeine consumption curbs rTMS-induced plasticity
Background: Caffeine is a widely used psychostimulant. In the brain, caffeine acts as a competitive, non-selective adenosine receptor antagonist of A1 and A2A, both known to modulate long-term potentiation (LTP), the cellular basis of learning and memory. Repetitive transcranial magnetic stimulation (rTMS) is theorized to work through LTP induction and can modulate cortical excitability as measured by motor evoked potentials (MEPs). The acute effects of single caffeine doses diminish rTMS-induced corticomotor plasticity. However, plasticity in chronic daily caffeine users has not been examined.
Method: We conducted a post hoc secondary covariate analysis from two previously published plasticity-inducing pharmaco-rTMS studies combining 10 Hz rTMS and D-cycloserine (DCS) in twenty healthy subjects.
Results: In this hypothesis-generating pilot study, we observed enhanced MEP facilitation in non-caffeine users compared to caffeine users and placebo.
Conclusion: These preliminary data highlight a need to directly test the effects of caffeine in prospective well-powered studies, because in theory, they suggest that chronic caffeine use could limit learning or plasticity, including rTMS effectiveness.
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TAGS
BRAIN PLASTICITYBRAIN RESEARCHCAFFEINELEARNINGNEUROBIOLOGYNEUROPLASTICITYNEUROSCIENCEOPEN ACCESSOPEN SCIENCESYNAPTIC PLASTICITY
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