High-frequency, low-intensity vibrations increase bone mass and muscle strength in upper limbs, improving autonomy in disabled children

[문형철]

휠체어를 타고 있는 아이들의 골밀도와 근력강화에 최적의 자극찾기에 대한 논문

고빈도, low-magnitude vibraion자극을 60Hz로 하루에 5분씩, 6개월 자극한 그룹에서 골밀도, 근력이 최고 회복

panic bird.....

High-frequency, low-intensity vibrations increase bone mass.pdf

Abstract

Background: Disuse osteoporosis in children is a progressive disease, which can affect quality of life. High-frequency, low-magnitude vibrations (HFLMV) act as anabolic signals for bone and muscle. 

- 아이들에게 disuse 골다공증은 진행성 질환이고 삶의 질에 큰 영향을 줌. 

- 고빈도, low- magnitude vibration자극은 뼈와 근육에 동화자극 신호로 작용함. 

Methods: A prospective, randomized double-blind and placebo controlled clinical trial to assess the efficacy and safety of regional HFLMV in  disabled children was performed. Sixty-five children, 6 to 9 year-old, were randomized into three groups: placebo, 60 Hz and 90 Hz. 

In the two active groups, a 0.3 g mechanical vibration was delivered to the radii and femora for 5 minutes each day.

Following the 6 months, the main outcome was bone mineral density (BMD) at the ultradistal radius (UDR), 33% radii (33%R) and femoral necks (FN). Secondary outcomes were area and BMC at the UDR, 33%R, and FN; grip force of the upper and lower limbs; motor function; and PedsQL eval‎uation. An intention-to-treat analysis was used. 

Results: Fifty-seven children (88%) completed the protocol. A significant increase was observed in the 60 Hz group relative to the other groups in BMD-UDR (p=0.011), grip force of the upper limbs (p=0.035), and “Daily activities item” (p=0.035). A mixed model to eval‎uate the response to intervention showed a stronger effect of 60 Hz, on patients with cerebral palsy, on UDR, and that between-subject variability significantly affected the response. There were no reported side effects of the intervention.

Discussion: This work provides evidence that regional HFLMV is an effective and safe strategy to improve bone mass, muscle strength, and possibly independence in children with motor disabilities.