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The inflammatory phase follows trauma to collagen fibres and lasts for 3-5 days, depending on the severity of the injury. Chemicals are released which produce pain, and there is bleeding in the tissues. This, together with fluid from damaged cells, produces swelling within the joint, putting pressure on nerve endings and causing more pain.
Rehabilitation time can be greatly reduced by appropriate treatment in this acute stage. This consists ofprotecting the injured part from further damage (e.g. the use of crutches), rest from activity involving the injured part, ice (never apply ice directly to the skin), compression, elevation and the administration of anti-inflammatory medication.
The repair phase is mediated by blood clotting over the damaged tissue. Blood platelets form a mesh to initiate healing. Also present in the blood clot are fibroblast cells, which proliferate and begin to lay down Type 3 (immature) collagen tissue, between 3-21 days after the injury. The use of electrotherapy in this phase has been shown to encourage fibroblast activity that ultimately provides a structurally stronger ligament.
The remodelling phase follows the repair phase and can last for up to a year. It involves maturation of collagen tissue from Type 3 to Type 1 and realignment of collagen tissue. When it is first laid down, the collagen tissue is haphazard and does not possess a lot of tensile strength. The ligament gradually becomes stronger through being subjected to controlled strain in a functional pattern, which aligns the fibres in a longitudinal fashion. Physiotherapy, in the form of controlled exercises progressing to functional activity, aid this process of remodelling.
Because the remodelling phase lasts for up to a year, there is a potential weakness in the ligament and a risk of re-injury. This risk is reduced by providing additional stability with a strapping, increasing the strength of muscles which also provide support to the joint, and by doing proprioceptive exercises to increase the patient's sense of joint positioning.