J Dent Res 88(3) 2009 Fluoride in Compomers and Future Caries 279
amalgam in this respect when amalgam is placed with a
fluoride-releasing bonding agent. Considering the results
presented here, together with our previously published results
on new restoration placement and replacement of existing
restorations (Soncini et al., 2007), our study suggests that
placement of compomer restorations in a high-risk population
results in more future dental needs compared with amalgam.
ACKNOWLEDGMENTS
The study was supported by the National Institute of Dental and
Craniofacial Research, Bethesda, MD, USA (U01 DE11886),
which also participated in the design and conduct of the study.
Trial Registration: Health Effects of Dental Amalgams in
Children, NCT00065988, http://www.clinicaltrials.gov/ct/show/
NCT00065988?order=1
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Figure. Rates of new caries after restoration placement, by treatment group,
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time model with proportional hazards, adjusted for age.
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