[과학만세] 메르스 uptodate 참고

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메르스에 대한 유언비어가 많아서 업투데이트 찾아봄.

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요약

1. 사람사이 감염은 비말감염이나 접촉 감염으로 추정.

2. 대부분 의료시설 내에서 감염됨. 2차감염의 경우 증상이 약하고 무증상인 경우가 많음.

3. R0값이 0.6~0.69로 전세계적 유행가능성은 적음.

4. WHO에 따르면 1139명 중 431명이 죽었다 (치사율 38%)

5. 그런데 이거는 경증환자들이 보고를 안하니까 좀 과장된 수치인듯 (1차감염의 치사율이 74%인데 2차감염 치사율이 21%라서)  

6. 나이 많을 수록 치사율 up

7. case 숫자가 작아서 신뢰하기는 좀 그렇네...

치사율 80%~90%는 구라인듯

공기감염도 구라인듯

Human-to-human transmission — Case clusters in the United Kingdom, Tunisia, Italy, and in healthcare facilities in Saudi Arabia, France, and Iran strongly suggest that human-to-human transmission occurs. The number of contacts infected by individuals with confirmed infections, however, appears to be limited. Secondary cases have tended to be milder than primary cases, and many secondary cases have been reported to be asymptomatic. Possible modes of transmission include droplet and contact transmission.

In a study that eval‎uated the transmissibility and epidemic potential of MERS-CoV based upon 55 laboratory-confirmed cases detected by late June 2013, the reproduction number (R0; defined as the average number of infections caused by one infected individual in a fully susceptible population) was estimated to be between 0.60 and 0.69. The finding of an R0 <1 suggests that MERS-CoV does not yet have pandemic potential. Others have pointed out that the R0 might be higher in the absence of infection control measures.

OUTCOMES — As of May 23, 2015, 431 of 1139 patients (38 percent) with laboratory-confirmed Middle East respiratory syndrome coronavirus (MERS-CoV) infection reported to the World Health Organization (WHO) have died. Because individuals with mild symptoms are less likely to be eval‎uated than patients with severe disease, those with MERS-CoV and mild disease might be underrepresented in published reports and reports from the WHO. The reported case-fatality rate might therefore be an overestimate. This hypothesis is supported by an analysis pointing out that 14 of 19 (74 percent) patients with infection detected through routine surveillance died compared with 5 of 24 (21 percent) of secondary cases.

In a study of 47 patients with MERS-CoV infection in Saudi Arabia, case-fatality rates rose with increasing age, from 39 percent in those younger than 50 years of age, to 48 percent in those younger than 60 years of age, to 75 percent in those aged 60 years or older. A separate analysis has shown similar findings.

[영국맛을살려야지]

coronavirus

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원내감염이 다수라 그냥 지나가다 휙 걸리지않는다 넘 걱정하지말길...

[pudding]

신원 밝혀진 19명의 확진 환자 중에 20대 여자 간호사 1명 있다. 19명 중 2명은 30대인데 한 명은 확진환자 아들이고, 다른 한 명은 같은 병동 환자다. 그 양반들 빼고는 전원 40대 이상 ㅇㅇ 젊은 사람도 걸리긴 걸린다.

[블랙베리-]

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