Primary progressive aphasia (PPA) & Logopenic progressive aphasia (LPA)

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Primary progressive aphasia (PPA) is a type of neurological syndrome in which language capabilities slowly and progressively become impaired. Although it was first described as solely impairment of language capabilities while other mental functions remain intact,[1] it is now recognized that many, if not most of those afflicted suffer impairment of memory, short term memory formation and loss of executive functions. It was first described as a distinct syndrome by M.-Marsel Mesulam in 1982.[2] Primary progressive aphasias have a clinical and pathological overlap with the frontotemporal lobar degeneration (FTLD) spectrum of disorders and Alzheimer's disease.

Logopenic progressive aphasia (LPA) is a form of primary progressive aphasia.[1] It is defined clinically by impairments in naming and sentence repetition.[2] It is similar to conduction aphasia and is associated with atrophy to the left posterior temporal cortex and inferior parietal lobule. It is suspected that an atypical form of Alzheimer's disease is the most common cause of logopenic progressive aphasia.[3][4]

Although patients with the logopenic variant of PPA are still able to produce speech, their speech rate may be significantly slowed down due to word retrieval‎ difficulty.[4] Over time, they may experience the inability to retain lengthy information, causing problems with understanding complex verbal information.[5] Some additional behavioral features include irritability, anxiety and agitation.[3]

Compared to other forms of primary progressive aphasia, the logopenic variant has been found to be associated with cognitive and behavioral characteristics. Studies have shown that patients with the logopenic variant perform significantly worse on tests of calculation than other primary progressive aphasia patients. Several logopenic variant patients, especially those with Alzheimer’s disease pathology, have also been found to perform poorly on memory tasks.[3]

Logopenic progressive aphasia is caused by damage to segregated brain regions, specifically the inferior parietal lobe and superior temporal regions. Difficulties in naming are produced from the thinning of the inferior parietal lobe. Damage to the dorsal pathways creates language deficiency in patients that is characteristic of logopenic progressive aphasia

https://en.wikipedia.org/wiki/Logopenic_progressive_aphasia

SDM-5 번역판(한국어판)에서 전두측두엽 주요 또는 경도 신경인지장애를 설명하는 671쪽 [진단적 특징] 부분에서

'행동변형과 3가지 언어 변형(의미적, 비어법적/비유창성, 그리고 논리 결핍적)' 부분의 번역 오류가 있음.

Semantic Apasia, Agrammatic  Apasia / Nonfiuent Aphasia, and Logopenic Apasia 를 의미하며

그에 대한 설명은 '신경언어장애(실어증): 언어표현장애, 언어이해장애' 등에 이해를 기반으로 해석을 해야 한다.

 Logopenic Apasia 는 naming and sentence repetition(명칭과 문장의 반복)을 특징으로 한다.

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Variant라는 단어의 경우 변이, 변형, 변종, 이형, 상이, 가변 등의 의미로 번역되는데 DSM-5번역에서는 상황에 따라 다르게 쓰지 않고 변형으로만 번역하고 있어서 의미 전달이 명화하지 않다. '변이'가 적절한 번역일 것으로 보인다.

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Logopenic Apasia의 경우 발화부족형 실어증으로 번역되는 것으로 검색되고 있음.