크론병(Crohn's disease) - 궤양성 장염

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The disease was named after Dr. Burill Crohn, who first described the condition in 1932.

Crohn's disease is one of the two main types of inflammatory bowel disease (IBD). The other is ulcerative colitis(UC; 얼써러티브 컬라이티스; 궤양 장염).


Ulcerative(얼써러티브)는 궤양(ulcer;얼써)이 있는, 궤양과 관련된 것을 뜻합니다. 궤양은 피부나 장기 표면에 생기는 흉터로, 자연적으로 치유되지 않는 상처를 말합니다.


Ulcerative colitis(UC; 얼써러티브 컬라이티스)는 대장과 직장의 점막에 염증과 궤양을 유발하는 만성 염증성 장 질환입니다.

UC는 염증성 장 질환의 일종으로, 전 세계에서 가장 흔한 형태의 염증성 장 질환입니다.

Crohn's disease is named after Dr. Burrill B. Crohn, an American gastroenterologist who first described the disease in 1932. Crohn was a physician at Mount Sinai Hospital in New York City.


How did Crohn's disease get its name?

Crohn and his colleagues published a paper in 1932 describing the disease.
Crohn was the first author listed on the paper.

People began referring to the disease as "Crohn's disease" after reading about it in a popular medical journal.



Indeterminate
"불확실한", "명확히 결정되지 않은", "미정의의"



Crohn’s Disease and Indeterminate Colitis

Victor W. Fazio

The knife cannot always have fresh fields for conquest; and although methods of practice may be modified and varied, and even improved to some extent, it must be within a certain limit.

–SIR JOHN ERICHSEN, Lancet. 1873;2:489


크론병은 소화관 모든 부위에서 발생할 수 있는 만성 염증성 장질환입니다.

크론병(Crohn's disease)은 유해한 박테리아에 지나치게 반응하는 면역 체계로 유발되는 만성적인 장 질환이다.

자가면역 질환으로 사람의 면역체계는 외부의 침입자로부터 자신을 보호하지만 자기 몸의 세포, 조직, 기관 등을 이물질로 인식하여 자기몸을 공격하여 질병을 유발한다.

염증성 장질환의 하나로 궤양성 장염과 비슷하다.

학자에 따라서는 궤양성 장염과 같은 질환으로 보기도 한다.


Crohn's disease is a type of inflammatory bowel disease (IBD) that causes swelling and irritation of the tissues, called inflammation, in the digestive tract. This can lead to belly pain, severe diarrhea, fatigue, weight loss and malnutrition.

Inflammation caused by Crohn's disease can affect different areas of the digestive tract in different people. Crohn's most commonly affects the end of the small intestine and the beginning of the large intestine. The inflammation often spreads into the deeper layers of the bowel.

Crohn's disease can be both painful and debilitating. Sometimes, it may lead to serious or life-threatening complications.

There's no known cure for Crohn's disease, but therapies can greatly reduce its symptoms and even bring about long-term remission and healing of inflammation. With treatment, many people with Crohn's disease can function well.