Figure 5. A schematic illustration representing the action of CRH in placenta.
A schematic illustration of representing the central action of CRH in placenta. A) High level of CRH stimulate or maintain PDGH activity and act as metabolic barrier of preventing prostaglandins (PGs) from crossing into the deciduas and myometrium. B) Low level of CRH do not stimulate or maintain PDGH activity. Then, PGs can cross into the deciduas and myometrium, where they could cause uterine contraction and labor. PGs represents prostaglandins.
Figure 5. A schematic illustration representing the action of CRH in the placenta.
A schematic illustration of representing the central action of CRH in the placenta. A) High level of CRH stimulates or maintains PDGH activity and acts as a metabolic barrier preventing prostaglandins (PGs) from crossing into the deciduas and myometrium. B) Low levels of CRH do not stimulate or maintain PDGH activity. Therefore, PGs can cross into the deciduas and myometrium, where they cause uterine contraction and labor.
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