초능력 세포

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초능력 세포가 물리적 장벽을 넘어서 교신한다

Psychic Cells Communicate across Physical Barrier By www.i-sis.org.uk Jun 29, 2014 - 2:48:20 AM

ISIS Report 23/06/14

Science of the Organism

Psychic Cells Communicate across Physical Barrier

몸안의 뉴런 신경세포는 다른 세포에 대해 물리적으로 분리된 회로를 따라서 여러 환경에 대해 반응한다;

가령 세포간의 구체적이지않은 교신은 1920년도 호 매원 박사 Dr Mae-Wan Ho 에 의해서 보고되었다.

그 기사에 완전히 설명된 버젼은 이시스 멤버 웹사이트 상에 올라왔는데, 이곳에  here 다운로드 된다.

이 글은 널리 회람하고 블로그에 다시 올려주세요, 허나 당신은 본래 기사의 웹주소를 명기해서 모든 링크를 보존해야한다. 이글이 유용함을 알게되면 우리가 운영하는 사회속의 과학 Science in Society 잡지에 가입해서 아이시스를 지원해 주세요. 또 주변에도 알려주길 바랍니다.

Neurons in culture respond readily to other cells in a physically separated compartment subjected to various treatments; such ‘non-substantial’ communication between cells has been documented since the 1920s Dr Mae-Wan Ho

A fully referenced and illustrated version of this article is posted on ISIS members website and is otherwise available for download here

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통상적인 세포생물학에 따르면 세포간 통신은 홀몬같은 퍼지는 요소를 통해서 멀리 전파하고 있으며, 짧은 거리는 시토킨을 통해 교신한다. 또 직접 접촉이 되는 것은 세포 부착과 반응 분자를 통해 교신한다.

세포는 여러형태의 접합과 신경결절을 통해 상호 교신한다. 신경결절은 세포를 직접 연결하며 또 다양한 단백질 종류를 포함한다.

아주 최근에는 핵산을 전파해서 상호교신분자의 종류를 추가하고 있다. Intercommunication via Circulating Nucleic Acids, SiS 42

이 부분은 통상의 학계에서 그렇게 인정하고 있지않다. 이미 알려져있거나 통상적으로 용인된 방식은 직접 물리적 접촉을 포함하며 세포사이를 전파하는 분자를 통해 교신하는 것이다.

그러나 빅터 챠반과 UCLA 대학 동료들은 세포가 멀리 떨어져있어도 교신을 하는 사실을 밝혀냈다.

According to conventional cell biology, cell-cell communication occurs via diffusible factors such as hormones for long distances, cytokines for shorter distances, and cell adhesion and receptor molecules for direct contact. Cells also intercommunicate via various junctions and synapses that directly connect the cells, involving many different kinds of proteins [1]. More recently, circulating nucleic acids have been added to the repertoire of intercommunication molecules [2] (Intercommunication via Circulating Nucleic Acids, SiS 42), though not yet generally accepted by the conventional community. All known or generally accepted mechanisms involve direct physical contact or connection between cells or molecules that can diffuse between cells.

But Victor Chaban and colleagues at University of California Los Angeles have found that cells physically separated are nevertheless able to communicate [3].

높은 수준의 비선형 교신을 시험하다 

Testing for “higher level non-linear communication”

연구팀은 물리적 접촉이나 퍼지는 분자를 요구하지않는 높은 수준의 비선형 교신을 시험하려고 계획했다. 그들은 인체의 세포간 통신의 중심인 뉴런을 사용했다. 그것들은 퍼지는 성질이 아닌 신호를 통해 다른 세포에대해 강인한 반응을 보여주곤한다, 그 말은 그런 류의 신호가 존재한다는 것이다.

The team had set out to test for “higher level non-linear communication” that does not require physical contact or diffusible molecules. They used neurons that are central to intercellular communication within the body, and therefore most likely to show robust responses to other cells via non-diffusible signals, it such signals exist.

돌살 루트 신결절, 즉 후근 신경절 DRG 감각 신경세포는 초기 상태로 유지될 수있다; 그것들은 다양한 감각 신호상에 이미 관측할 수있는 수준의 고도로 감각적인 세포들이다.  그 신경세포들은 ATP-sensitive P2X3 에 반응하는 수용기를 통해서 활성화되고 적응한다, 또 주변 신경절 상에서 캡사이친에 감각하는 capsaicin-sensitive TRPV1 같은 수용기를 통해서도 그렇다.

The dorsal root ganglia (DRG) sensory neurons can be maintained in primary culture; they are highly sensitive cells already used for investigations on various sensory signalling. These neurons can be activated and/or modulated via receptors such as the ATP-sensitive P2X3 and capsaicin-sensitive TRPV1 on their peripheral nerve terminals.

A ‘dish-in-dish’ cell culture system was devised, consisting of a small compartment in the middle of a bigger dish in which the DRG neurons were grown. The response of the DRG neurons was measured as intracellular calcium currents while ATP or capsaicin with and without estradiol were perfused into the outer compartment, into which were introduced normal DRG neurons, dying DRG neurons or abnormally behaving cells, such as cancer cells.

In order to make sure that the cells would not be disturbed by any other stray signals. The experiments were conducted in a new, nearly empty 30 000 sq ft basic science floor with no other active research labs, and in addition, the recordings were made in a Faraday cage to protect neurons from electromagnetic influence.

Large ‘psychic’ responses

The results were clear. The DRG cells in the inner compartment responded to ATP (10 mM) added to normal DRG cells in the outer compartment with a large spike of Ca²⁺ current detected on fluorescent imaging by preloading the cells with a Ca²⁺-sensitive fluorescent dye (see Figure 1 A, B). In the presence of estradiol (100 nM), the ATP response was reduced to less than half, as estradiol was washed out, the ATP response once again returned to normal. However, when neuroblastoma cells were present in the outer compartment, the DRG response to ATP was reduced to half, and estradiol had little or no effect (Fig. 1 C, D). Pretreatment with antagonists of P2X3 receptor or addition of Ca²⁺ chelator in Ca²⁺-free medium abolished the response, as consistent with the necessity for extracellular Ca²⁺ and P2X3 receptor for the Ca²⁺ current. The response to capsaicin (300 nM) was similar, and estradiol also reduced that response to less than half.

Figure 1   Response of DRG cells in Ca2+ current measured in nM. A, time course of typical response to ATP, attenuated after 5 min pretreatment with estradiol, and return to normal amplitude after washout of estradiol, B, average responses in the three periods represented in A; C, response of DRG cells after 12 h incubation with SH-SY5Y neuroblastoma cells in the outer compartment, D, average of responses in the three periods represented in C

When the outer compartment was filled with DRG neurons exposed to KCl to induce apoptosis (programmed cell death), the first ATP response was increased by 3-4 times the control with healthy DRG cells in the outer compartment (Figure 2 A), but no subsequent responses were produced (Fig. 2 B). Capsaicin (300 nM) stimulated typical responses with healthy DRG cells in the outer compartment (Fig. 2 C), but gave no response with apoptotic cells in the outer compartment (Fig. 2 D).

Figure 2   Response of DRG to ATP and capsaicin in the presence of normal cells (A, C) and apoptotic cells (B, D) in the outer compartment (see text for further details)

‘Psychic’ communication between cells

Thus the cells in the outer compartment were able to communicate with the physically separated cells in the central compartment, and not via a diffusible chemical in the cell medium. In other words, the authors have demonstrated a substantial ‘psychic’ communication between the cells, although they did not use the term. Instead, they appeal to some kind of “collective connectivity”. Actually, the results do not rule out airborne communication via gases or other volatile signalling molecules.

An obvious mechanism that the authors have not considered is communication between molecules and cells via electromagnetic signals, which I have proposed since the first 1993 edition of [4] The Rainbow and the Worm, The Physics of Organisms (ISIS publication). The proposal was by no means original, as empirical evidence for electromagnetic intercommunication between cells had existed since the 1920s in the work of Russian embryologist Alexander Gurwitsch (1874-1954) (reviewed in [5]), who discovered ‘mitogenic’ radiation in the ultraviolet range emitted by dividing cells that stimulated other cells to divide.

In a simple experiment, actively dividing yeast cells were placed in a closed quartz cuvette as a source of electromagnetic mitogenic signal inside a beaker filled with cells that have been growth-restricted by being kept cold for two hours previously. he entire beaker with quartz cuvette was wrapped in aluminium foil to exclude external electromagnetic radiation. A control identical beaker and cuvette were set up in which the cuvette and beaker were both filled with the growth-restricted yeast cells, and similarly wrapped in aluminium foil. The cell growth in both beakers was measured hourly. The results showed that cells in the experimental beaker, presumably receiving mitogenic signals from the growing culture, invariably started to grow and increase in cell number immediately, whereas cells in the control beaker lagged 3 to 4 hours behind [5].

There is increasing evidence that electromagnetic signalling is much more fundamental in living organisms than conventional chemical/biochemical signalling [4, 6, 7] (Living Rainbow H₂O, ISIS publication; Life is Water Electric, SiS 57), often preceding any biochemical changes. It is high time to devote more attention to electromagnetic signalling, as it will truly revolutionize our understanding of cell biology as well as our approach to health and disease.

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