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출처 : http://youngsig.netian.com/database/pharm-dosage/500drug.html
2000년 12월 18일자 약사신문에 게재되었던 500대 처방 의약품의 시장동향 중에서 일부(100대)를 게재합니다.
연구 업무에 도움 되시길 바랍니다.
단위 : 백만달러
순위 |
제품명 |
물질명 |
회사명 |
적응증 |
매출액 |
승인년도 |
||||||
99년 |
98년 |
97년 |
96년 |
|||||||||
1 |
Losec/Prilosec |
Omeprazole |
Astra-Zeneca |
Ulcers |
5909.0 |
5776.0 |
5055.8 |
4448.5 |
89.09.14 |
|||
2 |
Zocor |
Simvastatin |
Merck & Co. |
Cholesterol reduction |
4495.0 |
3945.0 |
3575.0 |
2799.5 |
91.12.23 |
|||
3 |
Lipitor |
Atovastatin Ca |
Warner-Lambert |
Cholesterol reduction |
3700.0 |
2200.0 |
865.0 |
- |
96.12.17 |
|||
4 |
Norvasc |
Amlodipine |
Pfizer |
Hypertension |
3030.0 |
2575.0 |
2217.0 |
1795.1 |
92.07.31 |
|||
5 |
Clarytin/Clarityne |
Loratadine |
Schering-Plough |
Allergies |
2700.0 |
2300.0 |
1726.0 |
1149.9 |
93.04.12 |
|||
6 |
Prozac |
Fluoxetine HCl |
Eli Lilly |
Depression |
2613.4 |
2812.0 |
2559.0 |
2356.4 |
87.12.29 |
|||
7 |
Renitec/Vasotec |
Enalapril malate |
Merck & Co. |
Hypertension |
2305.0 |
2400.0 |
2510.0 |
2535.4 |
85.12.24 |
|||
8 |
Seroxat/Paxil |
Paraxetine HCl |
SmithKline Beecham |
Depression |
2109.0 |
1757.0 |
1474.0 |
1157.9 |
92.12.29 |
|||
9 |
Zoloft |
Setraline HCl |
Pfizer |
Depression |
2034.0 |
1836.0 |
1507.0 |
1337.2 |
91.12.30 |
|||
10 |
Prevacid |
Lansoprazole |
Tap Pharm |
Ulcers |
1900.0 |
1350.0 |
730.0 |
339.5 |
95.05.10 |
|||
11 |
Zyprexa |
Olanzapine |
Eli Lilly |
Schizophrenia |
1885.0 |
1443.0 |
730.0 |
87.0 |
96.09.30 |
|||
12 |
Augmentin |
Amoxicillin |
SmithKline Beecham |
Infections |
1819.3 |
1598.0 |
1517.0 |
1423.1 |
84.08.06 |
|||
13 |
Epogen |
Epoetine alpha |
Amgen |
Red blood cell enhancement |
1760.0 |
1380.0 |
1160.7 |
1071.7 |
89.06.01 |
|||
14 |
Lipostat/Pravachol |
Pravastatin |
Bristol-Myers Squibb |
Cholesterol reduction |
1704.0 |
1643.0 |
1437.0 |
1069.2 |
91.10.31 |
|||
15 |
Ciproxin/Cipro |
Ciprofoxacin |
Bayer |
Infections |
1625.3 |
1403.0 |
1441.1 |
1200.9 |
87.10.22 |
|||
16 |
Procrit |
Epoetine alpha |
Johnson & Johnson |
Red blood cell enhancement |
1505.0 |
1363.0 |
1169.0 |
1010.4 |
90.12.31 |
|||
17 |
Celeblex |
Celecoxib |
Pharmacia Corp, Pfizer |
Osteoarthritis,rheumatoid arthritis |
1500.0 |
- |
- |
- |
98.12.31 |
|||
18 |
Taxol |
Paclitaxel |
Bristol-Myers Squibb |
Cancer, Ovarian |
1481.0 |
1206.0 |
941.0 |
813.3 |
92.12.29 |
|||
19 |
Cozaar |
Losartan |
Merck & Co. |
Hypertension |
1385.0 |
1060.0 |
681.0 |
339.0 |
95.04.14 |
|||
20 |
Sandimmun&Neoral |
Cyclosporin |
Norvatis |
Organ transplant rejection |
1339.3 |
1276.0 |
1254.0 |
1049.4 |
95.07.14 |
|||
21 |
Zithromax |
Azithromycin |
Pfizer |
Infections |
1333.0 |
1041.0 |
821.0 |
619.2 |
91.11.04 |
|||
22 |
Glucophage |
Metformin HCl |
Bristol-Myers Squibb |
Type II Diabetes |
1317.0 |
861.0 |
579.0 |
332.0 |
94.12.29 |
|||
23 |
Neupogen |
Filgrastim |
Amgen |
Neutropenia reductiom |
1260.0 |
1120.0 |
1055.7 |
1016.1 |
91.02.21 |
|||
24 |
Klacid?biaxin |
Clarithromycin |
Abbott |
Infections |
1250.0 |
1250.0 |
1300.0 |
1150.4 |
91.10.31 |
|||
25 |
Zestril |
Lisinopril |
Astra-Zeneca |
Hypertention |
1221.0 |
1122.0 |
1035.0 |
990.4 |
87.12.30 |
|||
26 |
Rocephin |
Ceftriaxone Na |
Aventis SA |
Infections |
1197.7 |
1179.0 |
1011.0 |
868.2 |
84.12.21 |
|||
27 |
Mevalotin |
Pravastatin |
Sankyo |
Cholesterol reduction |
1128.1 |
940.0 |
1406.7 |
1324.6 |
1988 |
|||
28 |
Premarin |
Conjugated estrogen |
American Home Product |
Menopause |
1090.0 |
1650.0 |
915.0 |
801.2 |
78.10.16 |
|||
29 |
Humulin |
Insulin |
Eli Lilly |
Diabetes |
1087.5 |
959.2 |
936.0 |
883.9 |
82.10.28 |
|||
30 |
Flovent |
Fluticasone propionate |
Glaxo Wellcome |
Asthma |
1079.0 |
825.3 |
516.6 |
444.2 |
96.03.27 |
|||
31 |
Imigran/Imitrex |
Sumatriptan succinate |
Glaxo Wellcome |
Migrane |
1058.0 |
1157.0 |
1085.7 |
884.1 |
92.12.28 |
|||
32 |
Fosamax |
Alendronate Na |
Merck & Co. |
Osteoporosis |
1045.0 |
775.0 |
532.0 |
281.9 |
95.09.29 |
|||
33 |
Zantac |
Ranitidine HCl |
Glaxo Wellcome |
Ulcers |
1037.0 |
1255.0 |
2255.0 |
3167.1 |
83.06.09 |
|||
34 |
Viagra |
Sildenafil citrate |
Pfizer |
Erectile dysfunction |
1033.0 |
788.0 |
- |
- |
98.03.27 |
|||
35 |
Diflucan |
Fluconazole |
Pfizer |
Infections, Fungal |
1002.0 |
916.0 |
881.0 |
910.1 |
90.01.29 |
|||
36 |
Prepulsid/Propulsid |
Cisapride |
Johnson & Johnson |
Ulcers |
975.0 |
968.0 |
1045.0 |
910.3 |
93.07.29 |
|||
37 |
Risperidal |
Risperidone |
Johnson & Johnson |
Psychosis |
970.0 |
860.0 |
848.0 |
700.2 |
93.12.29 |
|||
38 |
Adalat |
Nifedipine |
Bayer |
Hypertension |
954.2 |
1045.0 |
1101.0 |
1029.0 |
85.11.27 |
|||
39 |
Voltaren |
Diclofenac Na |
Norvatis |
Osteoarthritis,rheumatoid arthritis |
946.7 |
1083.0 |
1105.8 |
964.1 |
96.03.08 |
|||
40 |
Selevent |
Salmeterol xinafoate |
Glaxo Wellcome |
Asthma |
922.0 |
825.3 |
665.8 |
391.0 |
94.02.04 |
|||
41 |
Neurontin |
Gobapentin |
Warner Lambert |
Epilepsy |
913.0 |
514.0 |
292.0 |
231.0 |
93.12.29 |
|||
42 |
Pepcidin/Pepcid |
Famotidine |
Merck & Co. |
Ulcers |
910.0 |
1110.0 |
1180.0 |
1029.7 |
86.10.15 |
|||
43 |
Gaster |
Famotidine |
Yamanouchi |
Ulcers |
886.8 |
659.6 |
677.4 |
588.5 |
85.06.07 |
|||
44 |
Atrovent |
Ipratropium Br |
Boehringer-Ingelheim |
Asthma |
864.0 |
654.1 |
691.7 |
645.8 |
95.10.20 |
|||
45 |
Effexor |
Venlafaxine HCl |
American Home Product |
Depression |
860.0 |
529.0 |
403.2 |
234.0 |
93.12.28 |
|||
46 |
Prinivil |
Lisinopril |
Merck & Co. |
Hypertension |
815.0 |
690.0 |
585.0 |
485.1 |
87.12.29 |
|||
47 |
Depakote |
Divalproex Na |
Abbott |
Epilepsy |
805.0 |
645.0 |
520.0 |
388.1 |
83.03.10 |
|||
48 |
cardura |
Doxazosin mesylate |
Pfizer |
Benign prostate hypertrophy |
794.0 |
688.0 |
626.0 |
533.2 |
90.11.02 |
|||
49 |
Claxane/Lovenox |
Enoxaperin Na |
Rhone-Poulenc Rorer |
Deep-vein thrombosis |
760.0 |
613.3 |
462.2 |
350.2 |
93.03.29 |
|||
50 |
Allegra |
Fexofenadine HCl |
Hoechst |
Seasonal allergy rhinitis |
750.1 |
484.7 |
215.1 |
17.3 |
96.07.25 |
순위 |
제품명 |
물질명 |
회사명 |
적응증 |
매출액 |
승인년도 |
|||
99년 |
98년 |
97년 |
96년 |
||||||
51 |
Combivir |
Lamividine&zidovudine |
Glaxo Wellcome |
Infections, HIV |
736.0 |
442.5 |
34.4 |
- |
97.09.26 |
52 |
Pulmicort Turbuhaler |
Budesonide |
AstraZeneca |
Asthma |
730.0 |
689.9 |
643.9 |
619.1 |
97.06.24 |
53 |
Lupron |
Leuprolide acetate |
TAP Pharm. |
Cancer, prostate |
730.0 |
750.0 |
990.0 |
934.0 |
85.04.09 |
54 |
Roaccutane/Accutane |
Isotretinoin |
Aventis SA |
Acne |
705.9 |
559.1 |
451.3 |
358.2 |
82.05.07 |
55 |
Lamisil |
Terbinafine HCl |
Norvatis |
Infections, Fungal |
700.7 |
646.6 |
628.4 |
363.9 |
92.12.30 |
56 |
Zoladex |
Goserein acetate |
AstraZeneca |
Cancer, breast |
686.0 |
624.8 |
569.9 |
545.4 |
89.12.29 |
57 |
Zinnat/Ceftin |
Cefuroxime axetil |
Glaxo Wellcome |
Infections |
680.0 |
681.2 |
649.4 |
672.3 |
87.12.28 |
58 |
Zofran |
Ondansetron HCl |
Glaxo Wellcome |
Nausea & vomiting |
674.0 |
644.7 |
619.9 |
603.6 |
91.01.04 |
59 |
Zovirax |
Acyclovir |
Glaxo Wellcome |
Infection, HIV |
667.0 |
667.9 |
951.2 |
1332.2 |
82.03.29 |
60 |
Crixivan |
Indinavir sulfate |
Merck & Co. |
Infection, HIV |
665.0 |
675.0 |
582.0 |
188.0 |
96.03.13 |
61 |
Intron A |
Interferon-α-2b |
Schering-Plough |
Cancer&viral infection |
650.0 |
719.0 |
598.0 |
524.1 |
86.06.04 |
62 |
Zerit |
Stavudine |
Bristol-Myers Squibb |
Infections, HIV |
635.0 |
551.0 |
398.0 |
140.0 |
94.06.27 |
63 |
Avonex |
Interferon-β-a |
Biogen |
Relapsing Multiple sclerosis |
621.0 |
394.9 |
240.0 |
76.5 |
96.05.17 |
64 |
Diprivan |
Propofol |
AstraZeneca |
Anaesthesia |
608.0 |
651.3 |
568.2 |
571.6 |
89.10.02 |
65 |
BuSpar |
Buspiron HCl |
Bristol-Myers Squibb |
Anxiety |
605.0 |
531.0 |
443.0 |
370.1 |
96.09.29 |
66 |
Paraplatin |
Carboplatin |
Bristol-Myers Squibb |
Cancer, ovarian |
600.0 |
525.0 |
437.0 |
372.9 |
89.03.13 |
66 |
Mevacor |
Lovastatin |
Merck & Co. |
Cholesterol reduction |
600.0 |
745.0 |
1100.0 |
1255.7 |
87.08.31 |
66 |
Rezulin |
Troglitazone |
Warner Lambert |
Type II diabetes |
600.0 |
748.0 |
420.0 |
- |
97.01.29 |
69 |
Ventolin |
Albuterol sulfate |
Glaxo Wellcome |
Asthma |
596.0 |
629.8 |
641.2 |
772.5 |
91.05.01 |
70 |
Aredia |
Pamidronate |
Norvatis |
Hypercalcaemia |
588.0 |
390.9 |
246.7 |
122.0 |
91.10.31 |
71 |
Viracept |
Nelfinavir mesylate |
Agouron |
Infections, HIV |
585.0 |
530.1 |
57.0 |
- |
97.03.14 |
72 |
Hytrin |
Terazosin HCl |
Abbott |
Benign prostate hypertrophy |
580.0 |
646.0 |
620.0 |
543.9 |
87.08.07 |
73 |
Primaxin |
Imipenem-cilastatin |
Merck & Co. |
Infections |
575.0 |
525.0 |
530.0 |
555.0 |
90.12.13 |
74 |
Nolvadex |
Tamoxifen citrate |
AstraZeneca |
Cancer, breast |
573.0 |
523.7 |
501.1 |
543.5 |
77.12.30 |
75 |
Wellbutrin |
Bupropion |
Glaxo Wellcome |
Depression |
572.0 |
508.8 |
239.4 |
126.3 |
96.10.04 |
76 |
Zyrtec |
Cetrizine |
Pfizer |
Allergies |
552.0 |
416.0 |
265.0 |
146.0 |
95.12.08 |
77 |
Iscover/Plavix |
Clopidogrel hydrogensulfate |
Bristol-Myers Squibb |
Atherosclerotic events |
547.0 |
144.0 |
- |
- |
98.07.13 |
78 |
Engerix B |
Hepatitis B vaccine |
Smithkline Beecham |
Hepatitis B |
540.0 |
886.7 |
584.0 |
597.1 |
89.08.28 |
79 |
Flonase/Flixonase |
Fluticasonepropionate |
Glaxo Wellcome |
Allergies |
539.0 |
454.4 |
351.0 |
282.2 |
94.10.14 |
80 |
Hypnovel/Versed |
Midazolam HCl |
Aventis SA |
Anaesthesia |
536.4 |
514.3 |
431.3 |
361.8 |
85.12.20 |
81 |
Coumadin |
Wafarin Na |
DuPont-Merck |
Venous thrombosis |
535.0 |
500.0 |
500.0 |
- |
1954 |
82 |
Toprol-XL/Seloken |
Metoprolol succinate |
AstraZeneca |
Hypertension |
531.0 |
448.7 |
413.6 |
340.4 |
92.01.10 |
83 |
Rebetron |
Rivavirin&inteferonα2b |
Schering-Plough |
Hepatitis C |
530.0 |
100.0 |
- |
- |
98.06.03 |
84 |
Epivir |
Lamivudine |
Glaxo Wellcome |
Infections, HIV |
527.0 |
595.0 |
677.3 |
321.5 |
95.11.17 |
85 |
Cardizem |
Diltiazem |
Hoechst |
Hypertension |
522.0 |
814.3 |
825.7 |
792.4 |
82.11.05 |
86 |
Procardia XL |
Nifedipine |
Pfizer |
Hypertension |
521.0 |
714.0 |
822.0 |
1004.9 |
89.09.06 |
87 |
Sporanox |
Itraconazole |
Johnson & Johnson |
Infections, fungal |
515.0 |
567.0 |
537.0 |
615.1 |
92.09.11 |
88 |
Taxotere |
Docetaxel |
Rhone-Poulenc Rorer |
Cancer, breast |
514.5 |
380.4 |
252.6 |
77.7 |
96.05.14 |
89 |
Accupro/Accupril |
Quinapril HCl |
Warner Lambert |
Hypertension |
514.0 |
454.0 |
378.0 |
406.0 |
91.11.19 |
90 |
Nizoral |
Ketoconazole |
Johnson & Johnson |
Infections, fungal |
510.0 |
430.0 |
364.0 |
380.0 |
81.06.12 |
91 |
Tenormin/Tenoretic |
Atenolol |
AstraZeneca |
Hypertension |
509.0 |
500.5 |
551.9 |
650.1 |
81.08.19 |
92 |
Xalatan |
Latanoprost |
Pharmacia&Upjohn |
Ocular hypertension |
507.3 |
332.0 |
164.7 |
29.8 |
96.06.05 |
93 |
Ceredase&cerezyme |
Algulcerase |
Genzyme |
Gaucher's disease |
500.0 |
411.0 |
333.0 |
264.9 |
91.04.05 |
93 |
Capoten |
Captopril |
Bristol-Myers Squibb |
Hypertension |
500.0 |
636.0 |
795.0 |
1090.5 |
81.04.06 |
93 |
Singulair |
Montelukast Na |
Merck & Co. |
Asthma |
500.0 |
194.0 |
- |
- |
98.02.20 |
96 |
Xenical |
Orilistat |
Aventis SA |
Obesity |
499.2 |
40.0 |
- |
- |
98.07.29 |
97 |
Divan |
Valsartan |
Norvatis |
Hypertension |
493.3 |
282.0 |
79.9 |
5.5 |
96.12.23 |
98 |
Betaferon/Betaseron |
Inteferon β-1b |
Schering AG |
Multiple sclerosis |
483.6 |
409.2 |
386.8 |
307.2 |
93.07.23 |
99 |
Vioxx |
Rofecoxib |
Merck & Co |
Osteoarthritis |
472.0 |
- |
- |
- |
99.05.20 |
100 |
Harnal |
Tamsulosin |
Yamanouchi |
Benign prostate hypertrophy |
465.4 |
255.0 |
225.8 |
178.2 |