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A ‘Reverse Aging’ Guru’s Trail of Failed Businesses
Harvard geneticist David Sinclair aims to develop treatments for aging, but his companies have struggled to deliver
By Amy Dockser Marcus
Harvard geneticist David Sinclair’s seductive notion that aging is a treatable disease has helped companies he founded to raise more than $1 billion. The investors have almost nothing to show for it.
Four companies trying to develop longevity drugs have gone bankrupt or largely halted operations. Another four either haven’t yet tested their drugs or gene therapies in humans or have run only small-scale trials that make it difficult to know whether a drug will work.
Yet none of that has dented Sinclair’s status as the longevity business’s brightest star and chief salesman. Not only has he turned ideas from his own Harvard lab into commercial ventures, other entrepreneurs, attracted by his clout with both consumers and other scientists, have brought him in as a co-founder of their companies.
Sinclair also has co-founded companies that sell directly to consumers products such as antiaging dog chews, supplements and tests that purport to show one’s “biological age.”
중략........