136. 조혈모세포이식(골수이식)이란?

<center> <table style="width: 550px; text-align: left;" border="0" cellspacing="0" cellpadding="0"> <tbody> <tr> <td class="board_upline_cyan"></td></tr> <tr> <td class="board_titlebg_cyan_tt"> <h1 class="board_title"><font color="#1fda11"><span style="color: rgb(9, 0, 255);">조혈모세포이식(골수이식)</span></font></h1></td></tr> <tr> <td style="height: 2px; background-color: white;"></td></tr> <tr> <td style="text-align: center;"><font color="#1fda11"><br></font></td></tr> <tr> <td style="border-bottom-color: rgb(222, 222, 222); border-bottom-width: 1px; border-bottom-style: solid;"></td></tr> <tr> <td style="height: 15px;"></td></tr> <tr> <td><span style="color: rgb(9, 0, 255);"> </span><table style="width: 550px;" border="0" cellspacing="0" cellpadding="0"> <tbody> <tr> <td style="height: 200px; vertical-align: top;"><span style="color: rgb(9, 0, 255);"> </span><div id="ehealth"><span style="color: rgb(9, 0, 255);"> </span><h2><font color="#1fda11"><span style="color: rgb(9, 0, 255);">개요</span></font></h2> <p><b title="용어사전:조혈모세포이식" style="text-decoration: underline; cursor: pointer;" [안내]태그제한으로등록되지않습니다-xxxxxxonclick="window.open('http://health.mw.go.kr/Resource/Module/DictionarySearch/ContentView.aspx?Code=dic2_082','mywindow','width=490,height=750,resizable=0,toolbar=0,status=0,menubar=0')"><span style="font-size: 12pt;">조혈모세포이식</span></b><span style="font-size: 12pt;">(hematopoietic stem cell transplantation, HSCT)이란 과거 </span><span style="font-size: 12pt;"><b title="용어사전:골수" style="text-decoration: underline; cursor: pointer;" [안내]태그제한으로등록되지않습니다-xxxxxxonclick="window.open('http://health.mw.go.kr/Resource/Module/DictionarySearch/ContentView.aspx?Code=dic2_010','mywindow','width=490,height=750,resizable=0,toolbar=0,status=0,menubar=0')">골수</b></span><span style="font-size: 12pt;">를 활용하던 </span><span style="font-size: 12pt;"><b title="용어사전:골수" style="text-decoration: underline; cursor: pointer;" [안내]태그제한으로등록되지않습니다-xxxxxxonclick="window.open('http://health.mw.go.kr/Resource/Module/DictionarySearch/ContentView.aspx?Code=dic2_010','mywindow','width=490,height=750,resizable=0,toolbar=0,status=0,menubar=0')">골수</b></span><span style="font-size: 12pt;"> 이식(bone marrow transplantation, BMT)의 영역을 넘어서 현재는 </span><span style="font-size: 12pt;"><b title="용어사전:말초" style="text-decoration: underline; cursor: pointer;" [안내]태그제한으로등록되지않습니다-xxxxxxonclick="window.open('http://health.mw.go.kr/Resource/Module/DictionarySearch/ContentView.aspx?Code=dic2_028','mywindow','width=490,height=750,resizable=0,toolbar=0,status=0,menubar=0')">말초</b></span><span style="font-size: 12pt;">혈액(peripheral blood, PB)과 제대혈(cord blood, CB) 내에 존재하는 모든 형태의 조혈모세포를 이식원으로 활용하여 이식하는 것을 의미합니다. 조혈모세포이식은 초기에는 조직적합성항원(Human Lymphocyte Antigen, HLA)이 일치하는 형제간에만 시행되었지만 이식 면역학의 발전으로 현재는 비혈연간 이식 혹은 HLA 불일치 상황에서도 이식이 활발하게 이루어지고 있고 환자 자신의 </span><span style="font-size: 12pt;"><b title="용어사전:말초" style="text-decoration: underline; cursor: pointer;" [안내]태그제한으로등록되지않습니다-xxxxxxonclick="window.open('http://health.mw.go.kr/Resource/Module/DictionarySearch/ContentView.aspx?Code=dic2_028','mywindow','width=490,height=750,resizable=0,toolbar=0,status=0,menubar=0')">말초</b></span><span style="font-size: 12pt;">혈액조혈모세포(peripheral blood stem cell, PBSC)를 이용한 자가조혈모세포이식(autologous HSCT)도 표준화된 진료 방법의 하나로 자리 잡고 있습니다. </span><span style="font-size: 12pt;"><b title="용어사전:조혈모세포이식" style="text-decoration: underline; cursor: pointer;" [안내]태그제한으로등록되지않습니다-xxxxxxonclick="window.open('http://health.mw.go.kr/Resource/Module/DictionarySearch/ContentView.aspx?Code=dic2_082','mywindow','width=490,height=750,resizable=0,toolbar=0,status=0,menubar=0')">조혈모세포이식</b></span><span style="font-size: 12pt;">은 지난 50년간 비약적인 발전을 거듭하여 초기의 </span><span style="font-size: 12pt;"><b title="용어사전:골수" style="text-decoration: underline; cursor: pointer;" [안내]태그제한으로등록되지않습니다-xxxxxxonclick="window.open('http://health.mw.go.kr/Resource/Module/DictionarySearch/ContentView.aspx?Code=dic2_010','mywindow','width=490,height=750,resizable=0,toolbar=0,status=0,menubar=0')">골수</b></span><span style="font-size: 12pt;">이식의 국한된 개념에서 벋어나 백혈병으로 대표되는 백혈병, 재생불량성빈혈, 악성림프종은 물론 불응성 </span><span style="font-size: 12pt;"><b title="용어사전:자가면역질환" style="text-decoration: underline; cursor: pointer;" [안내]태그제한으로등록되지않습니다-xxxxxxonclick="window.open('http://health.mw.go.kr/Resource/Module/DictionarySearch/ContentView.aspx?Code=dic2_075','mywindow','width=490,height=750,resizable=0,toolbar=0,status=0,menubar=0')">자가면역질환</b></span><span style="font-size: 12pt;">, 고형암 등 다양한 영역에서 효과적이며 희망적인 치료 수단으로 자리 잡아가고 있습니다. </span></p> <p> <object width="550" height="339" title="골수이식의 개념" classid="clsid:d27cdb6e-ae6d-11cf-96b8-444553540000" codebase="http://fpdownload.macromedia.com/pub/shockwave/cabs/flash/swflash.cab#version=7,0,0,0" allowNetworking='internal' allowScriptAccess='sameDomain' type='application/x-shockwave-flash'><param name="allowNetworking" value="internal" /><param name="_cx" value="14552"><param name="_cy" value="8969"><param name="FlashVars" value=""><param name="Movie" value="http://health.mw.go.kr/AttachFiles/Content/Animation/s03_001_a43.swf"><param name="Src" value="http://health.mw.go.kr/AttachFiles/Content/Animation/s03_001_a43.swf"><param name="WMode" value="Transparent"><param name="Loop" value="-1"><param name="Quality" value="High"><param name="SAlign" value=""><param name="Menu" value="-1"><param name="Base" value=""><param name="AllowScriptAccess" value=""><param name="Scale" value="ShowAll"><param name="DeviceFont" value="0"><param name="EmbedMovie" value="0"><param name="BGColor" value=""><param name="SWRemote" value=""><param name="MovieData" value=""><param name="SeamlessTabbing" value="1"><param name="Profile" value="0"><param name="ProfileAddress" value=""><param name="ProfilePort" value="0"><param name="AllowFullScreen" value="false">  <object width="550" height="339" title="골수이식의 개념" data="http://health.mw.go.kr/AttachFiles/Content/Animation/s03_001_a43.swf" type="application/x-shockwave-flash" allowNetworking='internal' allowScriptAccess='sameDomain'> <param name="wmode" value="window"> <p> 골수이식의 개념</p> </object>   </object></p> <p><img alt="작성 및 감수 : 대한의학회_대한이식학회" src="https://img1.daumcdn.net/relay/cafe/original/?fname=http%3A%2F%2Fhealth.mw.go.kr%2FAttachFiles%2FContent%2Fproof%2Fs03_159.jpg"></p></div></td></tr> <tr> <td><img width="1" height="1" alt="" src="https://img1.daumcdn.net/relay/cafe/original/?fname=http%3A%2F%2Fhealth.mw.go.kr%2FResource%2FModule%2FContent%2FContentLogTracer.ashx%3FLinkServiceContentIdx%3D5329%26LinkServiceType%3D70%26CID%3D04D8B965BF"></td></tr></tbody></table></td></tr></tbody></table></center>