'당뇨성 족부궤양' 이제 세포로 치료 테고사이언스 '칼로덤', 적응증 추가

<DIV>< <TABLE class=roundTable> <TBODY class=pos_rel> <TR class=pos_rel> <TD class="cb pos_rel"> <xFORM id=bbsForm name=bbsForm method=get> <DIV class="bbs_contents " id=bbs_contents> <DIV class=bbs_contents_inbox> <DIV class="user_contents scroll" id=user_contents name="user_contents"> <TABLE class=protectTable> <TBODY> <TR> <TD> <P> <TABLE cellSpacing=0 cellPadding=0 width="100%" border=0> <TBODY> <TR> <TD class=f24 style="COLOR: #000000" align=middle><STRONG><SPAN style="FONT-SIZE: 14pt"><SPAN style="FONT-SIZE: 14pt"></SPAN></SPAN></STRONG></TD></TR> <TR> <TD class=f16 style="COLOR: #bc3223; PADDING-TOP: 15px" align=middle></TD></TR> <TR> <TD height=15></TD></TR> <TR> <TD class=news_text style="COLOR: #000000; LINE-HEIGHT: 1.6; TEXT-ALIGN: justify" vAlign=top align=left> <DIV class=news_text id=text style="COLOR: #000000; LINE-HEIGHT: 1.6; TEXT-ALIGN: justify"><SPAN style="FONT-SIZE: 14pt">바이오 벤처기업인 테고사이언스(대표 전세화)은 자사의 동종유래 피부세포 치료제 ‘칼로덤’이 당뇨성 족부궤양 적응증으로 식약청 추가 승인을 획득했다고 8일 밝혔다.</SPAN><BR><BR><SPAN style="FONT-SIZE: 14pt">이미 지난 2005년 2도 화상 치료제로 품목 승인을 받은 칼로덤은 전국의 화상치료센터에서 연간 1만2000장이 사용되고 있는 제품이다.</SPAN><BR><BR><SPAN style="FONT-SIZE: 14pt">테고사이언스에 따르면 칼로덤의 원료는 2001년 신생남아의 포피(foreskin: 포경수술시 절취된 피부조각)다. </SPAN><BR><BR><SPAN style="FONT-SIZE: 14pt">여기서 추출한 피부줄기세포가 2주 남짓의 배양 기간을 거치면 인체의 표피와 똑같은 막을 형성하며 이 막이 칼로덤 완제품으로 가공된다. </SPAN><BR><BR> <TABLE align=center> <TBODY> <TR> <TD></TD></TR></TBODY></TABLE><BR><SPAN style="FONT-SIZE: 14pt">이렇게 만들어진 칼로덤이 환자의 상처에 부착되면 수십, 수백 종의 단백질이 상처로 침투해 피부세포의 증식과 이동을 촉진시켜 상실된 피부가 재생된다. </SPAN><BR><BR><SPAN style="FONT-SIZE: 14pt">테고사이언스가 2009년에 실시한 제3상 임상실험에서 칼로덤은 12주째 100%의 완치율을 보였다. 반면 일반 바세린 거즈를 사용한 경우 완치율은 70%를 밑돌았다. </SPAN><BR><BR><SPAN style="FONT-SIZE: 14pt">또한 치료 기간 역시 22일 정도 짧았고 깊은 궤양일수록 상대적으로 더 좋은 효과가 있다는 것도 입증됐다는 것이 회사의 설명이다.</SPAN><BR><BR><SPAN style="FONT-SIZE: 14pt">테고사이언스 전세화 대표는 "칼로덤은 상처부위에서 피부각질세포의 증식과 이동을 촉진하는 동시에 세포가 자라고 이동할 수 있는 기질을 제공해 당뇨성 족부궤양을 치료한다"며 "임상시험에서도 완벽한 치료효과를 보였다"고 설명했다. </SPAN></DIV> <TR> <TD> 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