Montreal researchers discover how cancer cells resistant to drugs

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padding: 0px 0px 20px; zoom: 0; border-top-style: none; border-color: rgb(52, 78, 127);"><div class="bd" style="margin: 0px; padding: 0px; zoom: 0; font-size: 14px; font-family: Georgia, Times, 'Times New Roman', serif; line-height: 1.6em;"><p class="first">MONTREAL - Montreal researchers have discovered one of the ways developed by cancer cells to resist cancer treatments.</p><p style="margin-top: 11px;">Katherine Borden of the Institute for Research in Immunology and Cancer at the University of Montreal, and his team have identified a previously unknown form of multidrug resistance, glucuronidation of drugs.</p><p style="margin-top: 11px;">"As part of our research, we followed the path by which chemical is desensitization to drugs for up to a protein that regulates the reproduction of genetic information," said Dr. Borden. By disabling this protein, the researchers were able to restore the sensitivity of cancer cells to the drugs.</p><p style="margin-top: 11px;">The researcher said that this process of resistance is not the only one used by the cells, and the process can also be done very quickly, in a few weeks.</p><p style="margin-top: 11px;">However, she says that this discovery opens up promising advances in the fight against cancer.</p><p style="margin-top: 11px;">The results of this work have been published in the scientific journal "Cancer Research".</p></div></div></div></div></div><div class="yog-wrap yog-grid yog-16u" style="margin: 0px; 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margin-right: 0px; margin-bottom: 0px; padding: 0px; list-style: none; clear: both; zoom: 1; position: relative;"><li id="ugccmt-comment_1419036523302-9d1b4706-897a-40e2-9e20-1a6db2c8961b" class="ugccmt-cmt-item" style="margin: 0px; padding: 0px; clear: both;"><div id="ugccmt-comment_1419036523302-9d1b4706-897a-40e2-9e20-1a6db2c8961b_0_1_0" class="ugccmt-comment " style="margin: 0px 10px; padding: 17px 10px; border-top-width: 1px; border-top-style: solid; border-top-color: rgb(235, 235, 235); overflow: hidden; zoom: 1;"><div class="ugccmt-avatar-container" id="yui_3_9_1_1_1419081227787_635" style="margin: 0px 12px 0px 0px; padding: 0px; position: relative; float: left;"><a id="ugccmt-user-guidi_NCXKHJGH6VC357K6E35JYZZHMU" class="ugccmt-user-cmt-img" target="_blank" style="color: rgb(0, 87, 144); cursor: pointer;"><img id="ugccmt-user_1419036523302-9d1b4706-897a-40e2-9e20-1a6db2c8961b_NCXKHJGH6VC357K6E35JYZZHMU" class="" width="48" height="48" src="https://img1.daumcdn.net/relay/cafe/original/?fname=https%3A%2F%2Fs.yimg.com%2Fos%2Fmit%2Fmedia%2Fm%2Fbase%2Fimages%2Ftransparent-1093278.png" alt="Germain" style="border: 0px; background-image: url(https://s.yimg.com/dh/ap/social/profile/profile_b48.png); background-repeat: no-repeat;"></a></div><div class="ugccmt-info" id="yui_3_9_1_1_1419081227787_619" style="margin: 0px; padding: 0px; overflow: hidden;"><div class="ugccmt-rate" style="margin: 0px; padding: 0px; float: right; zoom: 1;"><span id="ugccmt-rate-pos_1419036523302-9d1b4706-897a-40e2-9e20-1a6db2c8961b" class="ugccmt-rating-positive ugccmt-voted" style="font-weight: bold; color: rgb(44, 152, 1); float: left; width: 28px; line-height: 20px; font-size: 11px; margin-right: 3px; text-align: right;">1</span><span class="ugccmt-accessibility-invisible" style="clip: rect(1px 1px 1px 1px); overflow: hidden; position: absolute !important; padding: 0px !important; border: 0px !important; height: 1px !important; width: 1px !important; display: none;">users liked this comment</span><a rel="nofollow" href="https://fr-ca.actualites.yahoo.com/chercheurs-montr%C3%A9alais-d%C3%A9couvrent-comment-cellules-canc%C3%A9reuses-r%C3%A9sistent-m%C3%A9dicaments-161959890.html#" class="ugccmt-sprite_bg ugccmt-sprite_img blue_thumb_up_lout" id="ugccmt-rate-tu_1419036523302-9d1b4706-897a-40e2-9e20-1a6db2c8961b" style="color: rgb(0, 87, 144); display: block; float: left; width: 20px; height: 22px; cursor: pointer; text-indent: -9999em; background-image: url(https://s.yimg.com/os/mit/media/m/comments/img/sprite-1637400.png); background-position: 0px 0px; background-repeat: no-repeat;">Please sign in to give a thumbs-up</a><a rel="nofollow" href="https://fr-ca.actualites.yahoo.com/chercheurs-montr%C3%A9alais-d%C3%A9couvrent-comment-cellules-canc%C3%A9reuses-r%C3%A9sistent-m%C3%A9dicaments-161959890.html#" class="ugccmt-sprite_bg ugccmt-sprite_img blue_thumb_down_lout" id="ugccmt-rate-td_1419036523302-9d1b4706-897a-40e2-9e20-1a6db2c8961b" style="color: rgb(0, 87, 144); display: block; float: left; width: 20px; height: 22px; cursor: pointer; text-indent: -9999em; background-image: url(https://s.yimg.com/os/mit/media/m/comments/img/sprite-1637400.png); background-position: -22px 0px; background-repeat: no-repeat;">Please sign in to give a thumbs down</a><span id="ugccmt-rate-neg_1419036523302-9d1b4706-897a-40e2-9e20-1a6db2c8961b" class="ugccmt-rating-negetive ugccmt-rating-zero" style="font-weight: bold; color: rgb(157, 157, 156); float: left; width: 28px; line-height: 20px; font-size: 11px; margin-left: 3px;">0</span><span class="ugccmt-accessibility-invisible" style="clip: rect(1px 1px 1px 1px); overflow: hidden; position: absolute !important; padding: 0px !important; border: 0px !important; height: 1px !important; width: 1px !important; display: none;">users don \ 't like this comment</span></div><cite class="ugccmt-comment-meta" style="font-style: normal; color: rgb(107, 107, 107); font-size: 11px; float: left; margin-bottom: 5px;"><a id="ugccmt-user-guidn_NCXKHJGH6VC357K6E35JYZZHMU" class="ugccmt-user-cmt" target="_blank" style="color: rgb(0, 87, 144); vertical-align: bottom;"><strong style="text-transform: capitalize;">Germain</strong></a> <span class="ugccmt-bull" style="font-size: 18px; line-height: 14px; color: rgb(155, 155, 155); vertical-align: bottom;"> •  </span><span class="ugccmt-timestamp" style="vertical-align: bottom; padding-left: 3px; color: rgb(126, 126, 126);"><abbr style="border: 0px; display: inline-block;">there 12:00</abbr></span> <a id="ugccmt-report-abuse_1419036523302-9d1b4706-897a-40e2-9e20-1a6db2c8961b" class="abuse" href="http://help.yahoo.com/l/cf/yahoo/comments/article_comments/comment-guidelines.html" rel="nofollow" style="color: rgb(0, 87, 144); vertical-align: bottom; border-left-width: 1px; border-left-style: solid; border-left-color: rgb(126, 126, 126); padding-left: 5px; margin-left: 2px;">Report abuse</a></cite><blockquote class="ugccmt-commenttext" style="margin-right: 5px; padding: 0px; color: rgb(51, 51, 51); clear: both; line-height: 1.4em; word-wrap: break-word; overflow: auto;">thank you</blockquote><a id="ugccmt-view-reply_1419036523302-9d1b4706-897a-40e2-9e20-1a6db2c8961b" href="https://fr-ca.actualites.yahoo.com/chercheurs-montr%C3%A9alais-d%C3%A9couvrent-comment-cellules-canc%C3%A9reuses-r%C3%A9sistent-m%C3%A9dicaments-161959890.html#" class="ugccmt-reply ugccmt-view-reply" rel="nofollow" style="color: rgb(0, 87, 144); display: inline-block; margin-top: 10px; font-size: 11px;"><span class="ugccmt-sprite_bg right_arrow ugccmt-sprite_img" style="display: block; float: left; width: 6px; height: 10px; margin-right: 5px; background-image: url(https://s.yimg.com/os/mit/media/m/comments/img/sprite-1637400.png); background-position: -13px -135px; background-repeat: no-repeat;"></span><span id="ugccmt-total-replies_1419036523302-9d1b4706-897a-40e2-9e20-1a6db2c8961b"></span>Reply</a></div></div></li><li id="ugccmt-comment_1419010069791-08be1daf-480b-46ed-b4eb-f80184674cca" class="ugccmt-cmt-item" style="margin: 0px; padding: 0px; clear: both;"><div id="ugccmt-comment_1419010069791-08be1daf-480b-46ed-b4eb-f80184674cca_5_6_10" class="ugccmt-comment " style="margin: 0px 10px; padding: 17px 10px; border-top-width: 1px; border-top-style: solid; border-top-color: rgb(235, 235, 235); overflow: hidden; zoom: 1;"><div class="ugccmt-avatar-container" id="yui_3_9_1_1_1419081227787_642" style="margin: 0px 12px 0px 0px; padding: 0px; position: relative; float: left;"><a id="ugccmt-user-guidi_SYJSBF4G33PRP3ZPEIYGJALRHY" class="ugccmt-user-cmt-img" target="_blank" style="color: rgb(0, 87, 144); cursor: pointer;"><img id="ugccmt-user_1419010069791-08be1daf-480b-46ed-b4eb-f80184674cca_SYJSBF4G33PRP3ZPEIYGJALRHY" class="" width="48" height="48" src="https://img1.daumcdn.net/relay/cafe/original/?fname=https%3A%2F%2Fs.yimg.com%2Fos%2Fmit%2Fmedia%2Fm%2Fbase%2Fimages%2Ftransparent-1093278.png" alt="Denis" style="border: 0px; background-image: url(https://socialprofiles.zenfs.com/images/b56bbc2a11cee18b41bb40b67d08c008_48.jpeg); background-repeat: no-repeat;"></a></div><div class="ugccmt-info" id="yui_3_9_1_1_1419081227787_623" style="margin: 0px; padding: 0px; overflow: hidden;"><div class="ugccmt-rate" style="margin: 0px; padding: 0px; float: right; zoom: 1;"><span id="ugccmt-rate-pos_1419010069791-08be1daf-480b-46ed-b4eb-f80184674cca" class="ugccmt-rating-positive ugccmt-voted" style="font-weight: bold; color: rgb(44, 152, 1); float: left; width: 28px; line-height: 20px; font-size: 11px; margin-right: 3px; text-align: right;">6</span><span class="ugccmt-accessibility-invisible" style="clip: rect(1px 1px 1px 1px); overflow: hidden; position: absolute !important; padding: 0px !important; border: 0px !important; height: 1px !important; width: 1px !important; display: none;">users liked this comment</span><a rel="nofollow" href="https://fr-ca.actualites.yahoo.com/chercheurs-montr%C3%A9alais-d%C3%A9couvrent-comment-cellules-canc%C3%A9reuses-r%C3%A9sistent-m%C3%A9dicaments-161959890.html#" class="ugccmt-sprite_bg ugccmt-sprite_img blue_thumb_up_lout" id="ugccmt-rate-tu_1419010069791-08be1daf-480b-46ed-b4eb-f80184674cca" style="color: rgb(0, 87, 144); display: block; float: left; width: 20px; height: 22px; cursor: pointer; text-indent: -9999em; background-image: url(https://s.yimg.com/os/mit/media/m/comments/img/sprite-1637400.png); background-position: 0px 0px; background-repeat: no-repeat;">Please sign in to give a thumbs-up</a><a rel="nofollow" href="https://fr-ca.actualites.yahoo.com/chercheurs-montr%C3%A9alais-d%C3%A9couvrent-comment-cellules-canc%C3%A9reuses-r%C3%A9sistent-m%C3%A9dicaments-161959890.html#" class="ugccmt-sprite_bg ugccmt-sprite_img blue_thumb_down_lout" id="ugccmt-rate-td_1419010069791-08be1daf-480b-46ed-b4eb-f80184674cca" style="color: rgb(0, 87, 144); display: block; float: left; width: 20px; height: 22px; cursor: pointer; text-indent: -9999em; background-image: url(https://s.yimg.com/os/mit/media/m/comments/img/sprite-1637400.png); background-position: -22px 0px; background-repeat: no-repeat;">Please sign in to give a thumbs down</a><span id="ugccmt-rate-neg_1419010069791-08be1daf-480b-46ed-b4eb-f80184674cca" class="ugccmt-rating-negetive ugccmt-voted-neg" style="font-weight: bold; color: rgb(203, 71, 0); float: left; width: 28px; line-height: 20px; font-size: 11px; margin-left: 3px;">10</span><span class="ugccmt-accessibility-invisible" style="clip: rect(1px 1px 1px 1px); overflow: hidden; position: absolute !important; padding: 0px !important; border: 0px !important; height: 1px !important; width: 1px !important; display: none;">user \ 's not like this comment</span></div><cite class="ugccmt-comment-meta" style="font-style: normal; color: rgb(107, 107, 107); font-size: 11px; float: left; margin-bottom: 5px;"><a id="ugccmt-user-guidn_SYJSBF4G33PRP3ZPEIYGJALRHY" class="ugccmt-user-cmt" target="_blank" style="color: rgb(0, 87, 144); vertical-align: bottom;"><strong style="text-transform: capitalize;">Denis</strong></a> <span class="ugccmt-bull" style="font-size: 18px; line-height: 14px; color: rgb(155, 155, 155); vertical-align: bottom;"> •  </span><span class="ugccmt-timestamp" style="vertical-align: bottom; padding-left: 3px; color: rgb(126, 126, 126);"><abbr style="border: 0px; display: inline-block;">19 hours ago</abbr></span> <a id="ugccmt-report-abuse_1419010069791-08be1daf-480b-46ed-b4eb-f80184674cca" class="abuse" href="http://help.yahoo.com/l/cf/yahoo/comments/article_comments/comment-guidelines.html" rel="nofollow" style="color: rgb(0, 87, 144); vertical-align: bottom; border-left-width: 1px; border-left-style: solid; border-left-color: rgb(126, 126, 126); padding-left: 5px; margin-left: 2px;">Report abuse</a></cite><blockquote class="ugccmt-commenttext" style="margin-right: 5px; padding: 0px; color: rgb(51, 51, 51); clear: both; line-height: 1.4em; word-wrap: break-word; overflow: auto;">Well Done !!!</blockquote><a id="ugccmt-view-reply_1419010069791-08be1daf-480b-46ed-b4eb-f80184674cca" href="https://fr-ca.actualites.yahoo.com/chercheurs-montr%C3%A9alais-d%C3%A9couvrent-comment-cellules-canc%C3%A9reuses-r%C3%A9sistent-m%C3%A9dicaments-161959890.html#" class="ugccmt-reply ugccmt-view-reply" rel="nofollow" style="color: rgb(0, 87, 144); display: inline-block; margin-top: 10px; font-size: 11px;"><span class="ugccmt-sprite_bg right_arrow ugccmt-sprite_img" style="display: block; float: left; width: 6px; height: 10px; margin-right: 5px; background-image: url(https://s.yimg.com/os/mit/media/m/comments/img/sprite-1637400.png); background-position: -13px -135px; background-repeat: no-repeat;"></span><span id="ugccmt-total-replies_1419010069791-08be1daf-480b-46ed-b4eb-f80184674cca">5</span> Responses</a></div></div></li><li id="ugccmt-comment_1419017986894-d2ee606d-a01d-4529-9d49-874ae9f0d88e" class="ugccmt-cmt-item" style="margin: 0px; padding: 0px; clear: both;"><div id="ugccmt-comment_1419017986894-d2ee606d-a01d-4529-9d49-874ae9f0d88e_2_4_3" class="ugccmt-comment " style="margin: 0px 10px; padding: 17px 10px; border-top-width: 1px; border-top-style: solid; border-top-color: rgb(235, 235, 235); overflow: hidden; zoom: 1;"><div class="ugccmt-avatar-container" id="yui_3_9_1_1_1419081227787_646" style="margin: 0px 12px 0px 0px; padding: 0px; position: relative; float: left;"><a id="ugccmt-user-guidi_4RYZGXDSKS3J37I25Z4UGVBH44" class="ugccmt-user-cmt-img" target="_blank" style="color: rgb(0, 87, 144); cursor: pointer;"><img id="ugccmt-user_1419017986894-d2ee606d-a01d-4529-9d49-874ae9f0d88e_4RYZGXDSKS3J37I25Z4UGVBH44" class="" width="48" height="48" src="https://img1.daumcdn.net/relay/cafe/original/?fname=https%3A%2F%2Fs.yimg.com%2Fos%2Fmit%2Fmedia%2Fm%2Fbase%2Fimages%2Ftransparent-1093278.png" alt="leplubo" style="border: 0px; background-image: url(https://s.yimg.com/dh/ap/social/profile/profile_b48.png); background-repeat: no-repeat;"></a></div><div class="ugccmt-info" id="yui_3_9_1_1_1419081227787_627" style="margin: 0px; padding: 0px; overflow: hidden;"><div class="ugccmt-rate" style="margin: 0px; padding: 0px; float: right; zoom: 1;"><span id="ugccmt-rate-pos_1419017986894-d2ee606d-a01d-4529-9d49-874ae9f0d88e" class="ugccmt-rating-positive ugccmt-voted" style="font-weight: bold; color: rgb(44, 152, 1); float: left; width: 28px; line-height: 20px; font-size: 11px; margin-right: 3px; text-align: right;">4</span><span class="ugccmt-accessibility-invisible" style="clip: rect(1px 1px 1px 1px); overflow: hidden; position: absolute !important; padding: 0px !important; border: 0px !important; height: 1px !important; width: 1px !important; display: none;">users liked this comment</span><a rel="nofollow" href="https://fr-ca.actualites.yahoo.com/chercheurs-montr%C3%A9alais-d%C3%A9couvrent-comment-cellules-canc%C3%A9reuses-r%C3%A9sistent-m%C3%A9dicaments-161959890.html#" class="ugccmt-sprite_bg ugccmt-sprite_img blue_thumb_up_lout" id="ugccmt-rate-tu_1419017986894-d2ee606d-a01d-4529-9d49-874ae9f0d88e" style="color: rgb(0, 87, 144); display: block; float: left; width: 20px; height: 22px; cursor: pointer; text-indent: -9999em; background-image: url(https://s.yimg.com/os/mit/media/m/comments/img/sprite-1637400.png); background-position: 0px 0px; background-repeat: no-repeat;">Please sign in to give a thumbs-up</a><a rel="nofollow" href="https://fr-ca.actualites.yahoo.com/chercheurs-montr%C3%A9alais-d%C3%A9couvrent-comment-cellules-canc%C3%A9reuses-r%C3%A9sistent-m%C3%A9dicaments-161959890.html#" class="ugccmt-sprite_bg ugccmt-sprite_img blue_thumb_down_lout" id="ugccmt-rate-td_1419017986894-d2ee606d-a01d-4529-9d49-874ae9f0d88e" style="color: rgb(0, 87, 144); display: block; float: left; width: 20px; height: 22px; cursor: pointer; text-indent: -9999em; background-image: url(https://s.yimg.com/os/mit/media/m/comments/img/sprite-1637400.png); background-position: -22px 0px; background-repeat: no-repeat;">Please sign in to give a thumbs down</a><span id="ugccmt-rate-neg_1419017986894-d2ee606d-a01d-4529-9d49-874ae9f0d88e" class="ugccmt-rating-negetive ugccmt-voted-neg" style="font-weight: bold; color: rgb(203, 71, 0); float: left; width: 28px; line-height: 20px; font-size: 11px; margin-left: 3px;">3</span><span class="ugccmt-accessibility-invisible" style="clip: rect(1px 1px 1px 1px); overflow: hidden; position: absolute !important; padding: 0px !important; border: 0px !important; height: 1px !important; width: 1px !important; display: none;">user \ 's not like this comment</span></div><cite class="ugccmt-comment-meta" style="font-style: normal; color: rgb(107, 107, 107); font-size: 11px; float: left; margin-bottom: 5px;"><a id="ugccmt-user-guidn_4RYZGXDSKS3J37I25Z4UGVBH44" class="ugccmt-user-cmt" target="_blank" style="color: rgb(0, 87, 144); vertical-align: bottom;"><strong style="text-transform: capitalize;">Leplubo</strong></a> <span class="ugccmt-bull" style="font-size: 18px; line-height: 14px; color: rgb(155, 155, 155); vertical-align: bottom;"> •  </span><span class="ugccmt-timestamp" style="vertical-align: bottom; padding-left: 3px; color: rgb(126, 126, 126);"><abbr style="border: 0px; display: inline-block;">17 hours ago</abbr></span> <a id="ugccmt-report-abuse_1419017986894-d2ee606d-a01d-4529-9d49-874ae9f0d88e" class="abuse" href="http://help.yahoo.com/l/cf/yahoo/comments/article_comments/comment-guidelines.html" rel="nofollow" style="color: rgb(0, 87, 144); vertical-align: bottom; border-left-width: 1px; border-left-style: solid; border-left-color: rgb(126, 126, 126); padding-left: 5px; margin-left: 2px;">Report abuse</a></cite><blockquote class="ugccmt-commenttext" id="yui_3_9_1_1_1419081227787_923" style="margin-right: 5px; padding: 0px; color: rgb(51, 51, 51); clear: both; line-height: 1.4em; word-wrap: break-word; overflow: auto;"><font id="yui_3_9_1_1_1419081227787_925"><font id="yui_3_9_1_1_1419081227787_926">Bravo, future millionaires, because the devil's advocate I can be, pharmaceutical companies will buy your discovery and make you disappear into anonymity quickly.</font><font id="yui_3_9_1_1_1419081227787_924">Realize the millions that they will lose if one day we find a way to control this disease ....</font></font><a class="ugccmt-expand" href="https://fr-ca.actualites.yahoo.com/chercheurs-montr%C3%A9alais-d%C3%A9couvrent-comment-cellules-canc%C3%A9reuses-r%C3%A9sistent-m%C3%A9dicaments-161959890.html#" rel="nofollow" style="color: rgb(0, 87, 144);">More</a></blockquote><a id="ugccmt-view-reply_1419017986894-d2ee606d-a01d-4529-9d49-874ae9f0d88e" href="https://fr-ca.actualites.yahoo.com/chercheurs-montr%C3%A9alais-d%C3%A9couvrent-comment-cellules-canc%C3%A9reuses-r%C3%A9sistent-m%C3%A9dicaments-161959890.html#" class="ugccmt-reply ugccmt-view-reply" rel="nofollow" style="color: rgb(0, 87, 144); 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padding: 0px; position: relative; float: left;"><a id="ugccmt-user-guidi_FKTMIOONXEBGJAVTSW64K2XXVM" class="ugccmt-user-cmt-img" target="_blank" style="color: rgb(0, 87, 144); cursor: pointer;"><img id="ugccmt-user_1419015361105-76df281c-a46b-4f50-b901-b9f3b72497fd_FKTMIOONXEBGJAVTSW64K2XXVM" class="" width="48" height="48" src="https://img1.daumcdn.net/relay/cafe/original/?fname=https%3A%2F%2Fs.yimg.com%2Fos%2Fmit%2Fmedia%2Fm%2Fbase%2Fimages%2Ftransparent-1093278.png" alt="Underworld" style="border: 0px; background-image: url(https://socialprofiles.zenfs.com/images/e7b337b2ab3cccf65a05afbfab848f7_48.png); background-repeat: no-repeat;"></a></div><div class="ugccmt-info" id="yui_3_9_1_1_1419081227787_631" style="margin: 0px; padding: 0px; overflow: hidden;"><div class="ugccmt-rate" style="margin: 0px; padding: 0px; float: right; zoom: 1;"><span id="ugccmt-rate-pos_1419015361105-76df281c-a46b-4f50-b901-b9f3b72497fd" class="ugccmt-rating-positive ugccmt-voted" style="font-weight: bold; color: rgb(44, 152, 1); float: left; width: 28px; line-height: 20px; font-size: 11px; margin-right: 3px; text-align: right;">7</span><span class="ugccmt-accessibility-invisible" style="clip: rect(1px 1px 1px 1px); overflow: hidden; position: absolute !important; padding: 0px !important; border: 0px !important; height: 1px !important; width: 1px !important; display: none;">users liked this comment</span><a rel="nofollow" href="https://fr-ca.actualites.yahoo.com/chercheurs-montr%C3%A9alais-d%C3%A9couvrent-comment-cellules-canc%C3%A9reuses-r%C3%A9sistent-m%C3%A9dicaments-161959890.html#" class="ugccmt-sprite_bg ugccmt-sprite_img blue_thumb_up_lout" id="ugccmt-rate-tu_1419015361105-76df281c-a46b-4f50-b901-b9f3b72497fd" style="color: rgb(0, 87, 144); display: block; float: left; width: 20px; height: 22px; cursor: pointer; text-indent: -9999em; background-image: url(https://s.yimg.com/os/mit/media/m/comments/img/sprite-1637400.png); background-position: 0px 0px; background-repeat: no-repeat;">Please sign in to give a thumbs-up</a><a rel="nofollow" href="https://fr-ca.actualites.yahoo.com/chercheurs-montr%C3%A9alais-d%C3%A9couvrent-comment-cellules-canc%C3%A9reuses-r%C3%A9sistent-m%C3%A9dicaments-161959890.html#" class="ugccmt-sprite_bg ugccmt-sprite_img blue_thumb_down_lout" id="ugccmt-rate-td_1419015361105-76df281c-a46b-4f50-b901-b9f3b72497fd" style="color: rgb(0, 87, 144); display: block; float: left; width: 20px; height: 22px; cursor: pointer; text-indent: -9999em; background-image: url(https://s.yimg.com/os/mit/media/m/comments/img/sprite-1637400.png); background-position: -22px 0px; background-repeat: no-repeat;">Please sign in to give a thumbs down</a><span id="ugccmt-rate-neg_1419015361105-76df281c-a46b-4f50-b901-b9f3b72497fd" class="ugccmt-rating-negetive ugccmt-rating-zero" style="font-weight: bold; color: rgb(157, 157, 156); float: left; width: 28px; line-height: 20px; font-size: 11px; margin-left: 3px;">0</span><span class="ugccmt-accessibility-invisible" style="clip: rect(1px 1px 1px 1px); overflow: hidden; position: absolute !important; padding: 0px !important; border: 0px !important; height: 1px !important; width: 1px !important; display: none;">users don \ 't like this comment</span></div><cite class="ugccmt-comment-meta" id="yui_3_9_1_1_1419081227787_922" style="font-style: normal; color: rgb(107, 107, 107); font-size: 11px; float: left; margin-bottom: 5px;"><a id="ugccmt-user-guidn_FKTMIOONXEBGJAVTSW64K2XXVM" class="ugccmt-user-cmt" target="_blank" style="color: rgb(0, 87, 144); vertical-align: bottom;"><strong style="text-transform: capitalize;">Underworld</strong></a> <span class="ugccmt-bull" style="font-size: 18px; line-height: 14px; color: rgb(155, 155, 155); vertical-align: bottom;"> •  </span><span class="ugccmt-timestamp" style="vertical-align: bottom; padding-left: 3px; color: rgb(126, 126, 126);"><abbr style="border: 0px; display: inline-block;">18 hours ago</abbr></span> <a id="ugccmt-report-abuse_1419015361105-76df281c-a46b-4f50-b901-b9f3b72497fd" class="abuse" href="http://help.yahoo.com/l/cf/yahoo/comments/article_comments/comment-guidelines.html" rel="nofollow" style="color: rgb(0, 87, 144); vertical-align: bottom; border-left-width: 1px; border-left-style: solid; border-left-color: rgb(126, 126, 126); padding-left: 5px; margin-left: 2px;">Report abuse</a></cite><blockquote class="ugccmt-commenttext" id="yui_3_9_1_1_1419081227787_921" style="margin-right: 5px; padding: 0px; color: rgb(51, 51, 51); clear: both; line-height: 1.4em; word-wrap: break-word; overflow: auto;"><font id="yui_3_9_1_1_1419081227787_920">awesome! <font id="yui_3_9_1_1_1419081227787_919">keep you are a team! </font>congratulations!</font></blockquote><a id="ugccmt-view-reply_1419015361105-76df281c-a46b-4f50-b901-b9f3b72497fd" href="https://fr-ca.actualites.yahoo.com/chercheurs-montr%C3%A9alais-d%C3%A9couvrent-comment-cellules-canc%C3%A9reuses-r%C3%A9sistent-m%C3%A9dicaments-161959890.html#" class="ugccmt-reply ugccmt-view-reply" rel="nofollow" style="color: rgb(0, 87, 144); display: inline-block; margin-top: 10px; font-size: 11px;"><span class="ugccmt-sprite_bg right_arrow ugccmt-sprite_img" style="display: block; float: left; width: 6px; height: 10px; margin-right: 5px; background-image: url(https://s.yimg.com/os/mit/media/m/comments/img/sprite-1637400.png); background-position: -13px -135px; background-repeat: no-repeat;"></span><span id="ugccmt-total-replies_1419015361105-76df281c-a46b-4f50-b901-b9f3b72497fd"></span>Reply</a></div></div></li></ul><div class="ugccmt-footer" id="yui_3_9_1_1_1419081227787_918" style="margin: 10px 0px; 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