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Outside Case Pathology Review - Details

• Details

Study Result

Narrative

Accession No: SHS-20-02502
SPECIMEN SUBMITTED:
S19-09620, 46 SLIDES; C19-04055, 13 SLIDES ADDED


DIAGNOSIS (MICROSCOPIC):
S19-09620; 11/06/2019
A. OMENTUM, OMENTECTOMY
-- INVOLVED BY MUCINOUS ADENOCARCINOMA
B. SPLEEN, SPLENECTOMY
-- MUCINOUS ADENOCARCINOMA, INVOLVING THE SURFACE OF THE SPLENIC
CAPSULE
-- NO PARENCHMYAL INVOLVEMENT
C. PERITONEUM, LEFT DIAPHRAGM, RESECTION
-- INVOLVED BY MUCINOUS ADENOCARCINOMA
D. ILEOCOLON ANASTOMOSIS, STOMA TAKEDOWN
-- MUCINOUS ADENOCARCINOMA, INVOLVING PERICOLONIC AND MESENTERIC
ADIPOSE TISSUE
-- ONE OF FIVE LYMPH NODES INVOLVED BY METASTATIC ADENOCARCINOMA
(1/5)
-- PERINEURAL INVASION IDENTIFIED
-- CARCINOMAIS PRESENT AT THE MESENTERIC/RADIAL MARGIN
-- PROXIMAL AND DISTAL RESECTION MARGIN ARE NEGATIVE FOR CARCINOMA
E. MESENTERY, LESSER SAC, NODULES, EXCISION
-- INVOLVED BY MUCINOUS ADENOCARCINOMA
F. PERITONEUM, LEFT GUTTER, RESECTION
-- INVOLVED BY MUCINOUS ADENOCARCINOMA
G. PERITONEUM, PELVIC, RESECTION
-- INVOLVED BY MUCINOUS ADENOCARCINOMA
H. GALLBLADDER, CHOLECYSTECTOMY
-- MUCINOUS ADENOCARCINOMA, INVOLVING THE SEROSAL SURFACE OF THE
GALLBLADDER
I. LIVER, SEGMENT 5, WEDGE RESECTION
-- LIVER CAPSULE INVOLVED BY MUCINOUS ADENOCARCINOMA
-- NO PARENCHYMAL INVOLVEMENT
J. LIVER, SEGMENT 4-8, WEDGE RESECTION
-- LIVER CAPSULE INVOLVED BY MUCINOUS ADENOCARCINOMA
-- NO PARENCHYMAL INVOLVEMENT
K. LYMPH NODE, LEFT LOBE, PEDICLE, DISSECTION
-- PREDOMINANTLY ACELLULAR MUCIN
-- NO LYMPHOID TISSUE IDENTIFIED
L. LYMPH NODE, PORTAL, DISSECTION
-- PREDOMINANTLY ACELLULAR MUCIN
-- NO LYMPHOID TISSUE IDENTIFIED
M. OMENTUM, LESSER, OMENTECTOMY
-- INVOLVED BY MUCINOUS ADENOCARCINOMA
N. COLON, SIGMOID, NODULE, EXCISION
-- INVOLVED BY MUCINOUS ADENOCARCINOMA
O. MESENTERY, NODULE, EXCISION
-- ACELLULAR MUCIN
P. PERITONEUM, RIGHT DIAPHRAGM, RESECTION
-- ACELLULAR MUCIN
Q. LIVER, SEGMENT 5, CAPSULE LESION, WEDGE RESECTION
-- INVOLVED BY MUCINOUS ADENOCARCINOMA
R. LIVER, SEGMENT 1, WEDGE RESECTION
-- INVOLVED BY MUCINOUS ADENOCARCINOMA

C19-04055; 11/21/2019
A. PLEURAL FLUID, RIGHT, CYTOLOGY
-- NEGATIVE FOR MALIGNANCY

OKONKWO/ESMAEILI SHANDIZ/MARTIN/SHEN

COMMENT: Thank you for the opportunity to review this case. The
pleural fluid (C19-04055) specimen was diagnosed by Dr. Brock Martin
(Cytopathology).

S19-09620; 11/06/2019
The ileocolonic stoma takedown (D) demonstrates mucinous
adenocarcinoma involving the pericolonic soft tissue. Additionally,
perineural invasion is identified. Overall, histologic sections show
marked multi-organ involvement by mucinous adenocarcinoma, including
the peritoneal, hepatic, and splenic surfaces (ypT4b).

C19-04055; 11/21/2019
The provided cytologic preparations and cell block sections from the
right pleural fluid show occasional reactive mesothelial cells in a
background of mixed inflammation. On provided immunohistochemical
stains, the mesothelial cells are highlighted by calretinin, while
stains for MOC31, CK20, and CDX2 are negative.

CLINICAL HISTORY: The patient is a 61-year-old male with cecal
adenocarcinoma s/p right hemicolectomy at an outside hospital (San
Francisco area) in 2017, found to have extensive peritoneal
carcinomatosis and currently receiving FOLFIRI/Avastin in 2019. He
received HIPEC in November 2019. At the request of Dr. Byrne Lee, 46
slides labeled S19-09620 are received courtesy of Dr. Vishwas Parekh
of City of Hope National Medical Center in Duarte, CA.


I have reviewed the specimen and agree with the interpretation
above. JEANNE SHEN, M.D. Electronically signed 2/10/2020 6:24 PM

There is no component information for this result.

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